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Details on Person Translocation of RIAM to plasma membrane

Class:Id	Reaction:354060
_displayName	Translocation of RIAM to plasma membrane
_doRelease	TRUE
_timestamp	2010-09-01 08:31:02
authored	[InstanceEdit:354193] Garapati, P V, 2008-06-16 17:13:06
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:354078] Garapati, P V, 2008-06-16 17:02:05
edited	[InstanceEdit:354193] Garapati, P V, 2008-06-16 17:13:06
input	[Complex:354126] RAP1:GTP [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:354081] APBB1IP [cytosol] [Homo sapiens] [SimpleEntity:179856] PI(4,5)P2 [plasma membrane]
literatureReference	[LiteratureReference:354123] Platelet integrins and immunoreceptors [LiteratureReference:354167] RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion [LiteratureReference:354139] Rap1 regulation of RIAM and cell adhesion
modified	[InstanceEdit:373931] Garapati, P V, 2008-07-18 08:43:41 [InstanceEdit:373946] Garapati, P V, 2008-07-22 08:39:45 [InstanceEdit:377700] Garapati, P V, 2008-09-16 06:34:55 [InstanceEdit:383279] Garapati, P V, 2008-11-24 15:57:36 [InstanceEdit:939266] Jupe, S, 2010-09-01 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Translocation of RIAM to plasma membrane
output	[Complex:354110] Rap1-GTP:PIP2:RIAM [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:354173] Activation of Rap1 by cytosolic GEFs [Homo sapiens] [Reaction:392831] Calcium and Diacylglycerol activate CalDAG-GEFs (RasGRPs) [Homo sapiens] [Reaction:939265] Activation of Rap1 by membrane-associated GEFs [Homo sapiens] [Reaction:392834] Activation of EPACs by cAMP [Homo sapiens] [Reaction:392831] Calcium and Diacylglycerol activate CalDAG-GEFs (RasGRPs) [Homo sapiens]
releaseDate	2008-12-17
reviewed	[InstanceEdit:377695] Shattil, SJ, 2008-09-16 06:21:39
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:387568] R-HSA-354060.2
summation	[Summation:354136] Upon the production of activated Rap1A at the plasma membran...
(hasEvent)	[Pathway:354192] Integrin signaling [Homo sapiens]
(precedingEvent)	[Reaction:354097] Activation of Talin [Homo sapiens]
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No pathways have been reviewed or authored by Translocation of RIAM to plasma membrane (354060)