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Details on Person Association of the XRCC4:DNA ligase IV complex with the DNA-PK:DNA synaptic complex

Class:Id	Reaction:353475
_displayName	Association of the XRCC4:DNA ligase IV complex with the DNA-PK:DNA synaptic complex
_doRelease	TRUE
_timestamp	2015-09-01 15:36:55
authored	[InstanceEdit:399969] Saxena, A, 2008-07-07 18:55:16
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:353491] Saxena, A, 2008-06-12 16:39:18
edited	[InstanceEdit:418967] D'Eustachio, P, 2009-04-27 17:09:41
inferredFrom	[Reaction:5693574] XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ [Homo sapiens]
input	[Complex:353450] DNA-PK: DNA synaptic complex with processed (ligatable) DNA [nucleoplasm] [Gallus gallus] [Complex:353467] XRCC4:DNA ligase IV complex [nucleoplasm] [Gallus gallus]
modified	[InstanceEdit:399968] D'Eustachio, P, 2009-03-23 22:14:23 [InstanceEdit:418476] D'Eustachio, P, 2009-04-22 20:40:00 [InstanceEdit:418618] D'Eustachio, P, 2009-04-24 15:53:07 [InstanceEdit:418955] D'Eustachio, P, 2009-04-27 15:38:34 [InstanceEdit:418966] D'Eustachio, P, 2009-04-27 17:13:45 [InstanceEdit:6793443] Orlic-Milacic, Marija, 2015-09-01 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Association of the XRCC4:DNA ligase IV complex with the DNA-PK:DNA synaptic complex
output	[Complex:353495] DNA-PK:XRCC4:DNA ligase IV:DNA complex associated with ligatable DNA ends [nucleoplasm] [Gallus gallus]
precedingEvent	[Reaction:353313] Removal of 3'-phosphoglycolate (PG) moiety from DSB ends [Gallus gallus] [Reaction:353265] Interaction between two DNA-PK:DNA complexes at opposing ends of DNA DSB [Gallus gallus]
releaseDate	2009-06-01
reviewed	[InstanceEdit:418616] Borowiec, JA, 2009-04-23 20:19:22
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:49591] Gallus gallus
stableIdentifier	[StableIdentifier:2016422] R-GGA-353475.3
summation	[Summation:418957] A complex consisting of XRCC4 and DNA ligase IV is recruited...
(hasEvent)	[Pathway:353423] Non-homologous end joining (NHEJ) [Gallus gallus]
(precedingEvent)	[Reaction:353298] Removal of repair proteins and ligation of the processed ends of the DNA double-strand break [Gallus gallus]
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No pathways have been reviewed or authored by Association of the XRCC4:DNA ligase IV complex with the DNA-PK:DNA synaptic complex (353475)