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Details on Person SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane
Class:Id Reaction:352385 _displayName SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane _doRelease TRUE _timestamp 2025-08-14 07:44:19 authored [InstanceEdit:352382] D'Eustachio, P, 2008-06-02 20:10:30 catalystActivity [CatalystActivity:352388] amino acid transmembrane transporter activity of SLC1A5 [plasma membrane] compartment [Compartment:876] plasma membrane created [InstanceEdit:352377] D'Eustachio, P, 2008-06-02 20:14:10 edited [InstanceEdit:352382] D'Eustachio, P, 2008-06-02 20:10:30 input [SimpleEntity:212615] L-Gln [extracellular region] [SimpleEntity:74113] Na+ [extracellular region] [SimpleEntity:29432] L-Ala [cytosol] [SimpleEntity:83910] Na+ [cytosol] literatureReference [LiteratureReference:352381] Neutral amino acid transporter ASCT2 displays substrate-induced Na+ exchange and a substrate-gated anion conductance [LiteratureReference:352378] Cloning of the sodium-dependent, broad-scope, neutral amino acid transporter Bo from a human placental choriocarcinoma cell line modified [InstanceEdit:352499] D'Eustachio, P, 2008-06-03 13:08:24 [InstanceEdit:602192] D'Eustachio, P, 2010-04-15 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9963210] Stephan, Ralf, 2025-08-13 [InstanceEdit:9963282] Stephan, Ralf, 2025-08-14 [InstanceEdit:9963335] Stephan, Ralf, 2025-08-14 [InstanceEdit:9963370] Stephan, Ralf, 2025-08-14 name SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane negativePrecedingEvent [NegativePrecedingEvent:9963231] Futile Cycle: SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine [NegativePrecedingEvent:9963283] Futile Cycle: SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane [NegativePrecedingEvent:9963326] Futile Cycle: SLC36A1-mediated uptake of glycine, proline, and alanine [NegativePrecedingEvent:9963366] Futile Cycle: SLC38A1 (ATA1)-mediated uptake of neutral amino acids [NegativePrecedingEvent:9963347] Futile Cycle: SLC38A2 (ATA2)-mediated uptake of neutral amino acids [NegativePrecedingEvent:9963324] Futile Cycle: SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine [NegativePrecedingEvent:9963344] Futile Cycle: SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine [NegativePrecedingEvent:9963353] Futile Cycle: SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol [NegativePrecedingEvent:9963348] Futile Cycle: SLC6A15-mediated amino acid uptake [NegativePrecedingEvent:9963407] Futile Cycle: SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol [NegativePrecedingEvent:9963382] Futile Cycle: SLC7A10-mediated uptake of small neutral amino acids [NegativePrecedingEvent:9963386] Futile Cycle: SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol [NegativePrecedingEvent:9963427] Futile Cycle: SLC7A8-mediated uptake of neutral amino acids output [SimpleEntity:29472] L-Gln [cytosol] [SimpleEntity:83910] Na+ [cytosol] [SimpleEntity:352036] L-Ala [extracellular region] [SimpleEntity:74113] Na+ [extracellular region] releaseDate 2008-06-30 reverseReaction
reviewed [InstanceEdit:352498] Jassal, Bijay, 2008-06-03 reviewStatus [ReviewStatus:9821382] five stars species [Species:48887] Homo sapiens stableIdentifier [StableIdentifier:360197] R-HSA-352385.3 summation [Summation:352387] SLC1A5, associated with the plasma membrane, mediates the ex... (hasEvent) [Pathway:352230] Amino acid transport across the plasma membrane [Homo sapiens] (precedingEvent) [NegativePrecedingEvent:9963273] Futile Cycle: SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane [NegativePrecedingEvent:9963274] Futile Cycle: SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane [NegativePrecedingEvent:9963279] Futile Cycle: SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane [NegativePrecedingEvent:9963288] Futile Cycle: SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane [NegativePrecedingEvent:9963297] Futile Cycle: SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane [NegativePrecedingEvent:9963299] Futile Cycle: SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane [NegativePrecedingEvent:9963302] Futile Cycle: SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane [NegativePrecedingEvent:9963309] Futile Cycle: SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane [NegativePrecedingEvent:9963314] Futile Cycle: SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane [NegativePrecedingEvent:9963319] Futile Cycle: SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane (replacementInstances) [_Deleted:602195] Deletion of instance: 352389 (reverseReaction) [Reaction:352379] SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane [Homo sapiens] (updatedInstance) [_UpdateTracker:9790779] Update Tracker - [Reaction:352385] SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane - v33:[addLiteratureReference]
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No pathways have been reviewed or authored by SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane (352385)
