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Details on Person SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine

Class:Id	Reaction:352182
_displayName	SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine
_doRelease	TRUE
_timestamp	2025-08-14 07:22:34
authored	[InstanceEdit:352382] D'Eustachio, P, 2008-06-02 20:10:30
catalystActivity	[CatalystActivity:9028795] amino acid transmembrane transporter activity of SLC38A5 [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:352159] D'Eustachio, P, 2008-05-31 19:54:14
crossReference	[DatabaseIdentifier:9960022] RHEA:71160 [DatabaseIdentifier:9960028] RHEA:71164 [DatabaseIdentifier:9960019] RHEA:71168 [DatabaseIdentifier:9960026] RHEA:71128 [DatabaseIdentifier:9960024] RHEA:71132
edited	[InstanceEdit:352382] D'Eustachio, P, 2008-06-02 20:10:30
input	[DefinedSet:352178] ligands of SLC38A5 [extracellular region] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:74113] Na+ [extracellular region]
literatureReference	[LiteratureReference:352141] Structure, function, and tissue expression pattern of human SN2, a subtype of the amino acid transport system N
modified	[InstanceEdit:352392] D'Eustachio, P, 2008-06-02 20:14:17 [InstanceEdit:352499] D'Eustachio, P, 2008-06-03 13:08:24 [InstanceEdit:564711] D'Eustachio, P, 2010-04-05 [InstanceEdit:9028796] Jassal, Bijay, 2017-11-10 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9960027] Stephan, Ralf, 2025-07-06 [InstanceEdit:9963210] Stephan, Ralf, 2025-08-13 [InstanceEdit:9963282] Stephan, Ralf, 2025-08-14
name	SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine
negativePrecedingEvent	[NegativePrecedingEvent:9963204] Futile Cycle: SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine [NegativePrecedingEvent:9963315] Futile Cycle: SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine [NegativePrecedingEvent:9963303] Futile Cycle: SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine [NegativePrecedingEvent:9963306] Futile Cycle: SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane [NegativePrecedingEvent:9963314] Futile Cycle: SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane
output	[DefinedSet:352175] ligands of SLC38A5 [cytosol] [SimpleEntity:351626] H+ [extracellular region] [SimpleEntity:83910] Na+ [cytosol]
precedingEvent	[Reaction:352364] SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine [Homo sapiens]
releaseDate	2008-06-30
reviewed	[InstanceEdit:352498] Jassal, Bijay, 2008-06-03
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:359730] R-HSA-352182.4
summation	[Summation:352185] SLC38A5 (SN2), associated with the plasma membrane, mediates...
(hasEvent)	[Pathway:352230] Amino acid transport across the plasma membrane [Homo sapiens]
(precedingEvent)	[NegativePrecedingEvent:9963329] Futile Cycle: SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine [NegativePrecedingEvent:9963332] Futile Cycle: SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine [NegativePrecedingEvent:9963338] Futile Cycle: SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine [NegativePrecedingEvent:9963344] Futile Cycle: SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine [NegativePrecedingEvent:9963362] Futile Cycle: SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine [NegativePrecedingEvent:9963369] Futile Cycle: SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine [NegativePrecedingEvent:9963595] Futile Cycle: SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine
(updatedInstance)	[_UpdateTracker:9780169] Update Tracker - [Reaction:352182] SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine - v63:[add_removeCatalystActivity]
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