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Details on Person SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine

Class:Id	Reaction:352174
_displayName	SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine
_doRelease	TRUE
_timestamp	2025-08-14 07:22:23
authored	[InstanceEdit:352382] D'Eustachio, P, 2008-06-02 20:10:30
catalystActivity	[CatalystActivity:352151] amino acid transmembrane transporter activity of SLC38A3 [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:352159] D'Eustachio, P, 2008-05-31 19:54:14
edited	[InstanceEdit:352382] D'Eustachio, P, 2008-06-02 20:10:30
input	[DefinedSet:352186] ligands of SLC38A3 [extracellular region] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:74113] Na+ [extracellular region] [SimpleEntity:74113] Na+ [extracellular region]
literatureReference	[LiteratureReference:352144] Primary structure, genomic organization, and functional and electrogenic characteristics of human system N 1, a Na+- and H+-coupled glutamine transporter [LiteratureReference:352141] Structure, function, and tissue expression pattern of human SN2, a subtype of the amino acid transport system N
modified	[InstanceEdit:352392] D'Eustachio, P, 2008-06-02 20:14:17 [InstanceEdit:352499] D'Eustachio, P, 2008-06-03 13:08:24 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9963210] Stephan, Ralf, 2025-08-13 [InstanceEdit:9963282] Stephan, Ralf, 2025-08-14
name	SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine
negativePrecedingEvent	[NegativePrecedingEvent:9963213] Futile Cycle: SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine [NegativePrecedingEvent:9963301] Futile Cycle: SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine [NegativePrecedingEvent:9963310] Futile Cycle: SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine [NegativePrecedingEvent:9963300] Futile Cycle: SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane [NegativePrecedingEvent:9963302] Futile Cycle: SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane
output	[DefinedSet:352169] ligands of SLC38A3 [cytosol] [SimpleEntity:351626] H+ [extracellular region] [SimpleEntity:83910] Na+ [cytosol] [SimpleEntity:83910] Na+ [cytosol]
precedingEvent	[Reaction:352364] SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine [Homo sapiens]
releaseDate	2008-06-30
reviewed	[InstanceEdit:352498] Jassal, Bijay, 2008-06-03
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360635] R-HSA-352174.3
summation	[Summation:352163] SLC38A3 (SN1), associated with the plasma membrane, mediates...
(hasEvent)	[Pathway:352230] Amino acid transport across the plasma membrane [Homo sapiens]
(precedingEvent)	[NegativePrecedingEvent:9963324] Futile Cycle: SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine [NegativePrecedingEvent:9963333] Futile Cycle: SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine [NegativePrecedingEvent:9963342] Futile Cycle: SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine [NegativePrecedingEvent:9963349] Futile Cycle: SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine [NegativePrecedingEvent:9963359] Futile Cycle: SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine [NegativePrecedingEvent:9963364] Futile Cycle: SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine [NegativePrecedingEvent:9963599] Futile Cycle: SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine
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