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Details on Person SLC38A4 (ATA3)-mediated uptake of arginine and lysine

Class:Id	Reaction:352136
_displayName	SLC38A4 (ATA3)-mediated uptake of arginine and lysine
_doRelease	TRUE
_timestamp	2025-08-14 07:44:38
authored	[InstanceEdit:352382] D'Eustachio, P, 2008-06-02 20:10:30
catalystActivity	[CatalystActivity:352130] amino acid transmembrane transporter activity of SLC38A4 [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:352132] D'Eustachio, P, 2008-05-30 21:48:16
edited	[InstanceEdit:352382] D'Eustachio, P, 2008-06-02 20:10:30
input	[DefinedSet:352128] ligands of SLC38A4 [extracellular region]
literatureReference	[LiteratureReference:352131] Evidence for the transport of neutral as well as cationic amino acids by ATA3, a novel and liver-specific subtype of amino acid transport system A
modified	[InstanceEdit:352392] D'Eustachio, P, 2008-06-02 20:14:17 [InstanceEdit:352499] D'Eustachio, P, 2008-06-03 13:08:24 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9963370] Stephan, Ralf, 2025-08-14
name	SLC38A4 (ATA3)-mediated uptake of arginine and lysine
negativePrecedingEvent	[NegativePrecedingEvent:9963423] Futile Cycle: SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine [NegativePrecedingEvent:9963375] Futile Cycle: SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane
output	[DefinedSet:352135] ligands of SLC38A4 [cytosol]
releaseDate	2008-06-30
reviewed	[InstanceEdit:352498] Jassal, Bijay, 2008-06-03
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:361307] R-HSA-352136.3
summation	[Summation:352133] SLC38A4 (ATA3), associated with the plasma membrane, mediate...
(hasEvent)	[Pathway:352230] Amino acid transport across the plasma membrane [Homo sapiens]
(precedingEvent)	[NegativePrecedingEvent:9963334] Futile Cycle: SLC38A4 (ATA3)-mediated uptake of arginine and lysine [NegativePrecedingEvent:9963354] Futile Cycle: SLC38A4 (ATA3)-mediated uptake of arginine and lysine [NegativePrecedingEvent:9963602] Futile Cycle: SLC38A4 (ATA3)-mediated uptake of arginine and lysine
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No pathways have been reviewed or authored by SLC38A4 (ATA3)-mediated uptake of arginine and lysine (352136)