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Details on Person SLC38A2 (ATA2)-mediated uptake of neutral amino acids

Class:Id	Reaction:352108
_displayName	SLC38A2 (ATA2)-mediated uptake of neutral amino acids
_doRelease	TRUE
_timestamp	2025-08-14 07:44:30
authored	[InstanceEdit:352382] D'Eustachio, P, 2008-06-02 20:10:30
catalystActivity	[CatalystActivity:352086] amino acid transmembrane transporter activity of SLC38A2 [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:352121] D'Eustachio, P, 2008-05-30 18:55:49
crossReference	[DatabaseIdentifier:9956837] RHEA:68238 [DatabaseIdentifier:9956846] RHEA:29285 [DatabaseIdentifier:9956843] RHEA:29577 [DatabaseIdentifier:9956819] RHEA:71385 [DatabaseIdentifier:9960018] RHEA:68242 [DatabaseIdentifier:9960021] RHEA:68230 [DatabaseIdentifier:9956831] RHEA:28969 [DatabaseIdentifier:9956823] RHEA:29265 [DatabaseIdentifier:9956844] RHEA:70001
edited	[InstanceEdit:352382] D'Eustachio, P, 2008-06-02 20:10:30
input	[DefinedSet:352091] ligands of SLC38A2 [extracellular region] [SimpleEntity:74113] Na+ [extracellular region]
literatureReference	[LiteratureReference:352090] Primary structure, functional characteristics and tissue expression pattern of human ATA2, a subtype of amino acid transport system A
modified	[InstanceEdit:352138] D'Eustachio, P, 2008-05-31 19:54:06 [InstanceEdit:352392] D'Eustachio, P, 2008-06-02 20:14:17 [InstanceEdit:352499] D'Eustachio, P, 2008-06-03 13:08:24 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9960027] Stephan, Ralf, 2025-07-06 [InstanceEdit:9963210] Stephan, Ralf, 2025-08-13 [InstanceEdit:9963282] Stephan, Ralf, 2025-08-14 [InstanceEdit:9963370] Stephan, Ralf, 2025-08-14
name	SLC38A2 (ATA2)-mediated uptake of neutral amino acids
negativePrecedingEvent	[NegativePrecedingEvent:9963233] Futile Cycle: SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine [NegativePrecedingEvent:9963202] Futile Cycle: SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine [NegativePrecedingEvent:9963272] Futile Cycle: SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine [NegativePrecedingEvent:9963308] Futile Cycle: SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane [NegativePrecedingEvent:9963321] Futile Cycle: SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane [NegativePrecedingEvent:9963384] Futile Cycle: SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu
output	[DefinedSet:352088] ligands of SLC38A2 [cytosol] [SimpleEntity:83910] Na+ [cytosol]
precedingEvent	[Reaction:352364] SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine [Homo sapiens]
releaseDate	2008-06-30
reviewed	[InstanceEdit:352498] Jassal, Bijay, 2008-06-03
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:358661] R-HSA-352108.3
summation	[Summation:352124] SLC38A2 (ATA2), associated with the plasma membrane, mediate...
(hasEvent)	[Pathway:352230] Amino acid transport across the plasma membrane [Homo sapiens]
(precedingEvent)	[NegativePrecedingEvent:9963330] Futile Cycle: SLC38A2 (ATA2)-mediated uptake of neutral amino acids [NegativePrecedingEvent:9963331] Futile Cycle: SLC38A2 (ATA2)-mediated uptake of neutral amino acids [NegativePrecedingEvent:9963343] Futile Cycle: SLC38A2 (ATA2)-mediated uptake of neutral amino acids [NegativePrecedingEvent:9963347] Futile Cycle: SLC38A2 (ATA2)-mediated uptake of neutral amino acids [NegativePrecedingEvent:9963356] Futile Cycle: SLC38A2 (ATA2)-mediated uptake of neutral amino acids [NegativePrecedingEvent:9963365] Futile Cycle: SLC38A2 (ATA2)-mediated uptake of neutral amino acids [NegativePrecedingEvent:9963368] Futile Cycle: SLC38A2 (ATA2)-mediated uptake of neutral amino acids
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No pathways have been reviewed or authored by SLC38A2 (ATA2)-mediated uptake of neutral amino acids (352108)