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Details on Person The plasma membrane transport protein SLC6A12 (BGT-1) mediat...

Class:IdSummation:352004
_displayNameThe plasma membrane transport protein SLC6A12 (BGT-1) mediat...
_timestamp2008-05-29 20:27:13
created[InstanceEdit:352012] D'Eustachio, P, 2008-05-29 20:27:07
textThe plasma membrane transport protein SLC6A12 (BGT-1) mediates the uptake of GABA (gamma-aminobutyrate) and betaine and, less efficiently, of diminobutyrate (DABA) and beta-alanine. Together with each amino acid molecule, 3 sodium ions and 2 chloride ions are taken up. In the body, SLC6A12 is expressed in the proximal tubules of the kidney and cells of the central nervous system (Rasola et al. 1995; Matskevitch et al. 1999).
(summation)[Reaction:352029] SLC6A12 (BGT-1)-mediated uptake of GABA and betaine [Homo sapiens]
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