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Details on Person Caspase-mediated cleavage of MST3

Class:Id	Reaction:351901
_displayName	Caspase-mediated cleavage of MST3
_doRelease	TRUE
_timestamp	2017-11-21 16:31:25
authored	[InstanceEdit:352235] Schulze-Osthoff, K, 2008-05-18 10:00:05
catalystActivity	[CatalystActivity:202853] cysteine-type endopeptidase activity of Caspase-3, Caspase-7 [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:351919] Matthews, L, 2008-05-28 22:38:42
edited	[InstanceEdit:351852] Matthews, L, 2008-05-27 07:43:39
input	[EntityWithAccessionedSequence:351829] STK24 [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:351841] Caspase activation of mammalian sterile 20-like kinase 3 (Mst3). Nuclear translocation and induction of apoptosis [LiteratureReference:9029657] An unbiased proteomic screen reveals caspase cleavage is positively and negatively regulated by substrate phosphorylation
modified	[InstanceEdit:351930] Matthews, L, 2008-05-28 22:51:50 [InstanceEdit:352259] Matthews, L, 2008-06-02 07:49:06 [InstanceEdit:353176] Matthews, L, 2008-06-12 00:23:53 [InstanceEdit:9029666] Orlic-Milacic, Marija, 2017-11-21 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Caspase-mediated cleavage of MST3
output	[EntityWithAccessionedSequence:351892] STK24(1-325) [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:351898] STK24(326-443) [cytosol] [Homo sapiens]
releaseDate	2008-06-30
reviewed	[InstanceEdit:350641] Ranganathan, S, 2008-06-11 19:13:33
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:358831] R-HSA-351901.3
summation	[Summation:351867] Caspase-mediated cleavage of Mst3 activates its intrinsic ki...
(hasEvent)	[Pathway:111465] Apoptotic cleavage of cellular proteins [Homo sapiens]
(precedingEvent)	[Reaction:351947] Nuclear translocation of catalytic domain of Mst3 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9780004] Update Tracker - [Reaction:351901] Caspase-mediated cleavage of MST3 - v64:[addLiteratureReference, add_removeCatalystActivity, modifyText]
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No pathways have been reviewed or authored by Caspase-mediated cleavage of MST3 (351901)