Query author contributions in Reactome
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Details on Person Once the basic components of the docking complex are assembl...
| Class:Id | Summation:351740 |
|---|---|
| _displayName | Once the basic components of the docking complex are assembl... |
| _timestamp | 2009-08-20 15:32:34 |
| created | [InstanceEdit:351767] Gillespie, ME, 2008-05-27 21:11:17 |
| literatureReference | [LiteratureReference:433007] Cryo-electron tomography of clathrin-coated vesicles: structural implications for coat assembly |
| modified | [InstanceEdit:432684] Gillespie, ME, 2009-08-14 [InstanceEdit:433008] Gillespie, ME, 2009-08-20 |
| text | Once the basic components of the docking complex are assembled with one end of AP-1 bound to cargo molecules, the other end binds to clathrin. Clathrin triskelions polymerize into hexagons and pentagons, forming a cage, which leads to membrane deformation. This polymerization step drives the sculpting of the vesicle. The number of clathrin triskelions required to sculpt a vesicle appears to be variable, but has been estimated to require 36 - 60 triskelions assocaited with 30 - 66 AP-1 complexes. Here a ~380 angstroms vesicle is represented with 48 clathrin triskelions and 52 AP-1 complexes. |
| (summation) | [Reaction:421831] trans-Golgi Network Coat Assembly [Homo sapiens] |
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No pathways have been reviewed or authored by Once the basic components of the docking complex are assembl... (351740)
