Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person Association of MRE11 and NBS1 leads to nuclear localization of MRN complex

Class:Id	Reaction:351412
_displayName	Association of MRE11 and NBS1 leads to nuclear localization of MRN complex
_doRelease	TRUE
_timestamp	2011-11-23 11:05:49
authored	[InstanceEdit:399969] Saxena, A, 2008-07-07 18:55:16
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:351413] Saxena, A, 2008-05-22 20:44:09
edited	[InstanceEdit:418967] D'Eustachio, P, 2009-04-27 17:09:41
input	[Complex:351422] MRE11-RAD50 complex [nucleoplasm] [Gallus gallus] [EntityWithAccessionedSequence:216923] NBS, Nijmegen breakage syndrome protein 1 homolog [nucleoplasm] [Gallus gallus]
literatureReference	[LiteratureReference:265795] The forkhead-associated domain of NBS1 is essential for nuclear foci formation after irradiation but not essential for hRAD50[middle dot]hMRE11[middle dot]NBS1 complex DNA repair activity [LiteratureReference:217187] The MRE11-RAD50-NBS1 complex accelerates somatic hypermutation and gene conversion of immunoglobulin variable regions [LiteratureReference:216980] Recombination repair pathway in the maintenance of chromosomal integrity against DNA interstrand crosslinks
modified	[InstanceEdit:351443] Saxena, A, 2008-05-22 20:44:57 [InstanceEdit:399968] D'Eustachio, P, 2009-03-23 22:14:23 [InstanceEdit:418476] D'Eustachio, P, 2009-04-22 20:40:00 [InstanceEdit:418618] D'Eustachio, P, 2009-04-24 15:53:07 [InstanceEdit:418966] D'Eustachio, P, 2009-04-27 17:13:45 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Association of MRE11 and NBS1 leads to nuclear localization of MRN complex
output	[Complex:217021] MRE11-RAD50-NBS1 complex [nucleoplasm] [Gallus gallus]
precedingEvent	[Reaction:351407] Association of MRE11 with RAD50 [Gallus gallus] [Reaction:217209] Generation of a DNA double strand break [Gallus gallus]
releaseDate	2009-06-01
reviewed	[InstanceEdit:418616] Borowiec, JA, 2009-04-23 20:19:22
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:49591] Gallus gallus
stableIdentifier	[StableIdentifier:2016147] R-GGA-351412.2
summation	[Summation:351414] MRE11-RAD50-NBS1 (MRN) is a ubiquitous and conserved nucleas...
(hasEvent)	[Pathway:217106] Chk1-controlled and DNA-damage induced centrosome duplication [Gallus gallus] [Pathway:351444] Recruitment of repair and signaling proteins to double-strand breaks [Gallus gallus]
(precedingEvent)	[Reaction:216941] Phosphorylation of Chk1 by ATR [Gallus gallus]
[Change default viewing format]

No pathways have been reviewed or authored by Association of MRE11 and NBS1 leads to nuclear localization of MRN complex (351412)