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Details on Person Spermine => N-acetylated spermine

Class:IdReaction:351207
_displayNameSpermine => N-acetylated spermine
_doReleaseTRUE
_timestamp2025-06-11 16:07:06
authored[InstanceEdit:351144] Gopinathrao, G, 2008-05-21 15:52:50
catalystActivity[CatalystActivity:351231] diamine N-acetyltransferase activity of SAT1 [cytosol]
compartment[Compartment:70101] cytosol
crossReference[DatabaseIdentifier:9955551] RHEA:33100
edited[InstanceEdit:179407] Gopinathrao, G, 2006-04-27 13:13:48
input[SimpleEntity:353560] SPN [cytosol]
[SimpleEntity:76183] Ac-CoA [cytosol]
internalReviewed[InstanceEdit:9955817] D'Eustachio, Peter, 2025-06-11
literatureReference[LiteratureReference:353571] Isolation and characterization of a cDNA clone that codes for human spermidine/spermine N1-acetyltransferase
[LiteratureReference:351205] Polyamines: metabolism and implications in human diseases
[LiteratureReference:8984557] Mechanistic and structural analysis of human spermidine/spermine N1-acetyltransferase
modified[InstanceEdit:351232] Gopinathrao, G, 2008-05-21 20:55:59
[InstanceEdit:351239] Gopinathrao, G, 2008-05-21 20:59:40
[InstanceEdit:352217] Gopinathrao, G, 2008-06-02 00:42:58
[InstanceEdit:353132] Gopinathrao, G, 2008-06-11 17:15:22
[InstanceEdit:353581] Gopinathrao, G, 2008-06-12 17:22:59
[InstanceEdit:354047] Gopinathrao, G, 2008-06-16 14:42:34
[InstanceEdit:377464] Gopinathrao, G, 2008-09-12 14:45:23
[InstanceEdit:377671] Gopinathrao, G, 2008-09-15 23:37:39
[InstanceEdit:565779] D'Eustachio, P, 2010-04-08
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9955584] D'Eustachio, Peter, 2025-06-10
[InstanceEdit:9955818] D'Eustachio, Peter, 2025-06-11
nameSpermine => N-acetylated spermine
spermine + acetyl-CoA => N(1)-acetylspermine + CoA + H(+)
output[SimpleEntity:353575] NASPN [cytosol]
[SimpleEntity:76194] CoA-SH [cytosol]
[SimpleEntity:70106] H+ [cytosol]
precedingEvent
previousReviewStatus[ReviewStatus:9821384] two stars
releaseDate2008-09-30
reviewed[InstanceEdit:377465] D'Eustachio, P, 2008-06-12 14:43:38
reviewStatus[ReviewStatus:9821385] four stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:377935] R-HSA-351207.3
structureModified[InstanceEdit:9955584] D'Eustachio, Peter, 2025-06-10
summation[Summation:9955560] Spermidine/spermine N1-acetyltransferase (SAT1, also known a...
(hasEvent)[Pathway:351200] Interconversion of polyamines [Homo sapiens]
(precedingEvent)[BlackBoxEvent:351229] N-acetylated spermine (cytosol)=>N-acetylated spermine (peroxisomal) [Homo sapiens]
(updatedInstance)[_UpdateTracker:9790591] Update Tracker - [Reaction:351207] Spermine => N-acetylated spermine - v33:[addOutput]
[_UpdateTracker:9964724] Update Tracker - [Reaction:351207] Spermine => N-acetylated spermine - v94:[add_removeSummation, removeLiteratureReference, removeOutput]
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No pathways have been reviewed or authored by Spermine => N-acetylated spermine (351207)