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Details on Person Caspase-mediated cleavage of MASK

Class:Id	Reaction:350651
_displayName	Caspase-mediated cleavage of MASK
_doRelease	TRUE
_timestamp	2017-11-17 22:16:15
authored	[InstanceEdit:352235] Schulze-Osthoff, K, 2008-05-18 10:00:05
catalystActivity	[CatalystActivity:114327] cysteine-type endopeptidase activity of Caspase-3 [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:350643] Matthews, L, 2008-05-20 07:53:59
edited	[InstanceEdit:351852] Matthews, L, 2008-05-27 07:43:39
input	[EntityWithAccessionedSequence:351918] MST4 [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:351858] Cloning of MASK, a novel member of the mammalian germinal center kinase III subfamily, with apoptosis-inducing properties
modified	[InstanceEdit:351919] Matthews, L, 2008-05-28 22:38:42 [InstanceEdit:352259] Matthews, L, 2008-06-02 07:49:06 [InstanceEdit:353176] Matthews, L, 2008-06-12 00:23:53 [InstanceEdit:353605] Matthews, L, 2008-06-12 21:52:15 [InstanceEdit:354011] Matthews, L, 2008-06-13 21:45:18 [InstanceEdit:9029450] Orlic-Milacic, Marija, 2017-11-17 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Caspase-mediated cleavage of MASK
output	[EntityWithAccessionedSequence:351855] MST4(1-305) [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:351903] MST4(306-416) [cytosol] [Homo sapiens]
precedingEvent	[Reaction:114252] Cleavage of Procaspase-3 by the apoptosome [Homo sapiens] [Reaction:114259] Cleavage of Procaspase‑9 to caspase‑9 [Homo sapiens] [Reaction:114419] Dissociation of Caspase-3 from DIABLO:XIAP:Caspase-3 [Homo sapiens] [Reaction:114306] SMAC binds XIAP:Caspase-3 [Homo sapiens] [Reaction:418845] Activation of caspase-3 [Homo sapiens] [Reaction:373700] Caspase-9 binds DCC:DIP13alpha complex [Homo sapiens]
releaseDate	2008-06-30
reviewed	[InstanceEdit:350641] Ranganathan, S, 2008-06-11 19:13:33
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360397] R-HSA-350651.3
summation	[Summation:351921] MASK is cleaved in vitro by caspase 3 . C-terminally trunca...
(hasEvent)	[Pathway:111465] Apoptotic cleavage of cellular proteins [Homo sapiens]
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No pathways have been reviewed or authored by Caspase-mediated cleavage of MASK (350651)