Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

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Details on Person nucleolus

Class:IdCompartment:350
_displayNamenucleolus
_timestamp2018-04-19 17:11:26
accession0005730
componentOf
definitionA small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
instanceOf
modified[InstanceEdit:160533] Schmidt, EE, 2005-03-23 05:24:35
[InstanceEdit:162607] Schmidt, EE, 2005-04-01 11:06:09
[InstanceEdit:171322] Schmidt, EE, 2006-02-06 10:50:16
[InstanceEdit:258122] Kanapin, EE, 2008-03-27 12:15:20
[InstanceEdit:357819] Kanapin, EE, 2008-06-18 10:45:39
[InstanceEdit:376438] Kanapin, EE, 2008-09-08 10:23:04
[InstanceEdit:383393] Kanapin, AA, 2008-11-26 13:49:44
[InstanceEdit:396309] Kanapin, EE, 2009-03-09 13:26:57
[InstanceEdit:422569] Kanapin, EE
[InstanceEdit:436347] Kanapin, EE
[InstanceEdit:447572] Kanapin, EE
[InstanceEdit:526073] Kanapin, AA
[InstanceEdit:528085] Kanapin, AA
[InstanceEdit:615500] Kanapin, AA
[InstanceEdit:797782] Kanapin, AA
[InstanceEdit:937668] Yung, CK
[InstanceEdit:1042299] Yung, CK
[InstanceEdit:1220942] Yung, CK
[InstanceEdit:1301009] Yung, CK
[InstanceEdit:1301023] Yung, CK
[InstanceEdit:1552540] Yung, CK
[InstanceEdit:1996004] Yung, CK
[InstanceEdit:2132408] Weiser, JD
[InstanceEdit:2133145] Weiser, JD
[InstanceEdit:2266118] Weiser, JD
[InstanceEdit:2266147] Weiser, JD
[InstanceEdit:2454362] Weiser, JD
[InstanceEdit:2455542] Weiser, JD
[InstanceEdit:2587907] Weiser, JD
[InstanceEdit:3132285] Weiser, JD
[InstanceEdit:3445953] Weiser, JD
[InstanceEdit:4341211] Weiser, JD
[InstanceEdit:5083267] Weiser, JD
[InstanceEdit:5263134] Weiser, JD
[InstanceEdit:8949923] D'Eustachio, Peter, 2016-12-01
[InstanceEdit:9644776] Wu, G, 2019-04-20
[InstanceEdit:9658105] Weiser, JD, 2019-08-09
[InstanceEdit:9666277] Weiser, JD, 2019-11-04
[InstanceEdit:9666277] Weiser, JD, 2019-11-04
[InstanceEdit:9676538] Cook, Justin, 2020-02-17
[InstanceEdit:9689214] Cook, Justin, 2020-05-15
[InstanceEdit:9715950] Shorser, Solomon, 2021-02-17
[InstanceEdit:9730069] Shorser, Solomon, 2021-05-05
[InstanceEdit:9750511] Weiser, JD, 2021-08-11
[InstanceEdit:9758049] Weiser, JD, 2021-11-08
[InstanceEdit:9767446] Wright, Adam, 2022-02-25
[InstanceEdit:9773560] Weiser, Joel, 2022-05-04
[InstanceEdit:9910546] Weiser, Joel, 2024-05-14
[InstanceEdit:9917761] Weiser, Joel, 2024-08-09
[InstanceEdit:9926777] Weiser, Joel, 2024-11-03
[InstanceEdit:9939260] Weiser, Joel, 2025-02-21
[InstanceEdit:9948590] Weiser, Joel, 2025-05-21
[InstanceEdit:9963890] Weiser, Joel, 2025-08-15
[InstanceEdit:9970828] Weiser, Joel, 2025-10-31
[InstanceEdit:9983368] Weiser, Joel, 2026-02-22
[InstanceEdit:9989188] Weiser, Joel, 2026-05-15
namenucleolus
referenceDatabase[ReferenceDatabase:1] GO
surroundedBy
(compartment)[SimpleEntity:9935785] ATP [nucleolus]
[Complex:9683761] SUMO-p-N dimer [nucleolus] [Human SARS coronavirus]
[Complex:9694659] N dimer [nucleolus] [Severe acute respiratory syndrome coronavirus 2]
[Complex:9727894] NPM1:SUMO-p-Ncap [nucleolus] [Homo sapiens]
[Complex:9930037] TRAMP complex [nucleolus] [Homo sapiens]
[Complex:9935789] RNA exosome [nucleolus] [Homo sapiens]
[Complex:9935806] EXOSC10:C1D:MPHOSPH6 [nucleolus] [Homo sapiens]
[Complex:9935811] Exosome core complex [nucleolus] [Homo sapiens]
[Complex:9935815] TRAMP:RNA exosome [nucleolus] [Homo sapiens]
[DefinedSet:9935832] TENT4A,B [nucleolus] [Homo sapiens]
List all 73 refering instances
(componentOf)[Compartment:348] fibrillar center
[Compartment:360] dense fibrillar component
[Compartment:362] granular component
[GO_CellularComponent:17901] RNA polymerase I complex
[GO_CellularComponent:21609] RNA polymerase I transcription regulator complex
[GO_CellularComponent:81871] nucleolar ribonuclease P complex
[GO_CellularComponent:161073] RENT complex
[GO_CellularComponent:161714] nucleolar chromatin
[GO_CellularComponent:171848] box H/ACA snoRNP complex
[GO_CellularComponent:258335] small-subunit processome
List all 18 refering instances
(surroundedBy)[Compartment:360] dense fibrillar component
[Compartment:362] granular component
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No pathways have been reviewed or authored by nucleolus (350)