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Details on Person ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage

Class:IdLiteratureReference:349453
_displayNameATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage
_timestamp2008-05-07 23:07:01
author[Person:200710] Chen, L
[Person:349460] Gilkes, DM
[Person:349447] Pan, Y
[Person:173480] Lane, WS
[Person:68704] Chen, J
created[InstanceEdit:349466] Matthews, L, 2008-05-07 22:49:21
journalEMBO J
modified[InstanceEdit:349490] Matthews, L, 2008-05-07 23:04:44
pages3411-22
pubMedIdentifier16163388
titleATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage
volume24
year2005
(literatureReference)[EntityWithAccessionedSequence:349441] p-S346,S367,S403-MDM4 [nucleoplasm] [Homo sapiens]
[Complex:6804723] Ub:p-S342,S367,S403-MDM4 [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:6804725] Ub,p-S346,S367,S403-MDM4 [nucleoplasm] [Homo sapiens]
[Summation:349443] CHEK2 (Chk2) kinase is required for phosphorylation of MDM4 ...
[Pathway:264460] MDM2-mediated degradation of Mdmx [Homo sapiens]
[Reaction:349426] Phosphorylation of MDM4 by CHEK2 [Homo sapiens]
[Reaction:349455] Phosphorylation of MDM4 by ATM [Homo sapiens]
[Reaction:6804724] MDM2 ubiquitinates phosphorylated MDM4 [Homo sapiens]
[Pathway:6804757] Regulation of TP53 Degradation [Homo sapiens]
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