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Details on Person UniProt:Q9TZI1 cerk-1
| Class:Id | ReferenceGeneProduct:3445787 |
|---|---|
| _chainChangeLog | chain:1-549 added on Fri February 6 2015 |
| _displayName | UniProt:Q9TZI1 cerk-1 |
| _timestamp | 2025-08-15 22:16:50 |
| chain | chain:1-549 |
| checksum | DE95737555534EEB |
| comment | FUNCTION Catalyzes the phosphorylation of ceramide to form ceramide 1-phosphate (By similarity). C.elegans contain specific sphingoid bases, which are unique or different in structure compared to the sphingoid bases found in other animals. Two examples of these distinctive compounds are: 15-methylhexadecasphinganine and 15-methylhexadecasphing-4-enine (PubMed:30155209).CATALYTIC ACTIVITY an N-acylsphing-4-enine + ATP = an N-acylsphing-4-enine 1-phosphate + ADP + H(+)CATALYTIC ACTIVITY an N-acyl-15-methylhexadecasphing-4-enine + ATP = an N-acyl-15-methylhexadecasphing-4-enine-1-phosphate + ADP + H(+)PATHWAY Lipid metabolism; sphingolipid metabolism. |
| created | [InstanceEdit:3445779] Weiser, JD |
| description | recommendedName: Ceramide kinase 1 ecNumber: 2.7.1.138 |
| geneName | cerk-1 T10B11.2 |
| identifier | Q9TZI1 |
| isSequenceChanged | FALSE |
| keyword | ATP-binding Kinase Lipid metabolism Nucleotide-binding Reference proteome Sphingolipid metabolism Transferase |
| modified | [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5618415] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:9015733] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 [InstanceEdit:9963647] Weiser, Joel, 2025-08-15 |
| name | cerk-1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | CERK_CAEEL |
| sequenceLength | 549 |
| species | [Species:68320] Caenorhabditis elegans |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q9TZI1 cerk-1 (3445787)
