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Details on Person DBC1 binds SIRT1

Class:Id	Reaction:3371537
_displayName	DBC1 binds SIRT1
_doRelease	TRUE
_timestamp	2014-11-20 02:54:56
authored	[InstanceEdit:4793943] Shamovsky, V, 2013-10-28
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:3371552] Shamovsky, V, 2013-05-13
edited	[InstanceEdit:5324627] Shamovsky, V, 2014-02-17
input	[EntityWithAccessionedSequence:427531] SIRT1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:3371569] p-T454-DBC1 [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:3371421] DBC1 is a negative regulator of SIRT1 [LiteratureReference:3371462] Negative regulation of the deacetylase SIRT1 by DBC1 [LiteratureReference:3371488] The SIRT1 modulators AROS and DBC1 regulate HSF1 activity and the heat shock response
modified	[InstanceEdit:4793943] Shamovsky, V, 2013-10-28 [InstanceEdit:5082424] Shamovsky, V, 2013-11-05 [InstanceEdit:5083129] Shamovsky, V, 2013-11-05 [InstanceEdit:5148862] Shamovsky, V, 2013-11-18 [InstanceEdit:5324681] Shamovsky, V, 2014-02-17 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	DBC1 binds SIRT1
output	[Complex:3371545] p-T454-DBC1:SIRT1 [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:3371567] DBC1 is phosphorylated by ATM/ART [Homo sapiens]
releaseDate	2014-03-12
reviewed	[InstanceEdit:5324628] Pani, Bibhusita, 2014-02-17
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5645106] R-HSA-3371537.2
summation	[Summation:3371574] SIRT1 is a (NAD+)-dependent deacetylase that was reported to...
(hasEvent)	[Pathway:3371453] Regulation of HSF1-mediated heat shock response [Homo sapiens]
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No pathways have been reviewed or authored by DBC1 binds SIRT1 (3371537)