Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person HSF1 [cytosol]

Class:IdEntityWithAccessionedSequence:3371452
_displayNameHSF1 [cytosol]
_timestamp2014-11-20 04:11:43
compartment[Compartment:70101] cytosol
created[InstanceEdit:3371552] Shamovsky, V, 2013-05-13
endCoordinate529
nameHSF1
Heat shock transcription factor 1
HSTF 1
Heat shock factor protein 1
referenceEntity[ReferenceGeneProduct:56710] UniProt:Q00613 HSF1 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:5648447] R-HSA-3371452.1
startCoordinate1
(hasComponent)[Complex:4793919] HSF1:HSP90:PTGES3 [cytosol] [Homo sapiens]
[Complex:5324677] HSF1:HSP90:HDAC6:VCP:PTGES3 [cytosol] [Homo sapiens]
[Complex:9646339] HSP90:HSF1 [cytosol] [Homo sapiens]
[Complex:9857081] HSF1:HSPA1A,B [cytosol] [Homo sapiens]
(input)[Reaction:3371435] Constitutive phosphorylation by GSK3 [Homo sapiens]
[Reaction:3371531] Constitutive phosphorylation by pERK1/2 [Homo sapiens]
[Reaction:3371591] Trimerization of cytosolic HSF1 [Homo sapiens]
[Reaction:4793911] MAPKAPK2 phosphorylates HSF1 [Homo sapiens]
[BlackBoxEvent:9857091] HSF1 is activated by phosphorylation, translocation to the nucleus, and trimerization [Homo sapiens]
(output)[Reaction:3371586] Dissociation of cytosolic HSF1:HSP90 complex [Homo sapiens]
[Reaction:5324632] Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates [Homo sapiens]
[Reaction:9857076] Oxidized DNAJA1 binds HSPA1A,B (HSP70) displacing HSF1 [Homo sapiens]
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No pathways have been reviewed or authored by HSF1 [cytosol] (3371452)