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Details on Person HSP40:HSP70:ADP:nascent protein [cytosol]

Class:Id	Complex:3371441
_displayName	HSP40:HSP70:ADP:nascent protein [cytosol]
_timestamp	2016-08-25 00:04:05
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:3371552] Shamovsky, V, 2013-05-13
hasComponent	[CandidateSet:3299408] HSP70 proteins [cytosol] [Homo sapiens] [SimpleEntity:29370] ADP [cytosol] [OtherEntity:1799333] nascent polypeptide with signal sequence [cytosol] [CandidateSet:3371594] HSP40s [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:3371541] Peptide-binding sites as revealed by the crystal structures of the human Hsp40 Hdj1 C-terminal domain in complex with the octapeptide from human Hsp70 [LiteratureReference:3371577] Interaction between hsp70 and hsp40, eukaryotic homologues of DnaK and DnaJ, in human cells expressing mutant-type p53 [LiteratureReference:3371474] Heteromeric complexes of heat shock protein 70 (HSP70) family members, including Hsp70B', in differentiated human neuronal cells
modified	[InstanceEdit:5618133] Shamovsky, Veronica, 2014-08-18 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:8936973] Shamovsky, Veronica, 2016-08-25
name	HSP40:HSP70:ADP:nascent protein
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8906799] R-HSA-3371441.1
(hasComponent)	[Complex:3371457] STIP1:HSP90:HSP40:HSP70:ADP:unfolded protein [cytosol] [Homo sapiens]
(input)	[Reaction:3371503] STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein [Homo sapiens] [Reaction:3371506] HSP40:HSP70:ADP:unfolded protein [cytosol]->STIP1:HSP90:HSP40:HSP70:ADP:unfolded protein [cytosol]
(output)	[Reaction:3371422] ATP hydrolysis by HSP70 [Homo sapiens]
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No pathways have been reviewed or authored by HSP40:HSP70:ADP:nascent protein [cytosol] (3371441)