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Details on Person Soluble TNF-α binds TNFR1

Class:IdReaction:3371353
_displayNameSoluble TNF-α binds TNFR1
_doReleaseTRUE
_timestamp2022-06-30 05:18:18
authored[InstanceEdit:3371406] Shamovsky, V, 2013-05-13
compartment[Compartment:876] plasma membrane
[Compartment:984] extracellular region
[Compartment:70101] cytosol
created[InstanceEdit:3371404] Shamovsky, V, 2013-05-13
edited[InstanceEdit:3632865] Shamovsky, V, 2013-05-28
input[Complex:3371370] TNF-α trimer, soluble form [extracellular region] [Homo sapiens]
[Complex:5634181] TNFRSF1A:BAG4 [plasma membrane] [Homo sapiens]
literatureReference[LiteratureReference:140945] Human tumor necrosis factor-alpha receptor. Purification by immunoaffinity chromatography and initial characterization.
modified[InstanceEdit:3465520] Shamovsky, V, 2013-05-17
[InstanceEdit:3465577] Shamovsky, V, 2013-05-17
[InstanceEdit:3597633] Shamovsky, V, 2013-05-22
[InstanceEdit:3632866] Shamovsky, V, 2013-05-28
[InstanceEdit:5657734] Shamovsky, V, 2014-12-16
[InstanceEdit:5675041] Shamovsky, V, 2015-02-15
[InstanceEdit:6792553] Shamovsky, Veronica, 2015-08-25
[InstanceEdit:9794240] Shamovsky, Veronica, 2022-06-30
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameSoluble TNF-α binds TNFR1
output[EntityWithAccessionedSequence:5212670] BAG4 [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:5212670] BAG4 [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:5212670] BAG4 [cytosol] [Homo sapiens]
[Complex:3371397] soluble TNF-α:TNFR1 [plasma membrane] [Homo sapiens]
precedingEvent
releaseDate2013-06-11
reviewed[InstanceEdit:3597630] Pop, Cristina, Salvesen, Guy S., 2013-05-22
[InstanceEdit:6792551] Wajant, Harald, 2015-08-25
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:3654232] R-HSA-3371353.4
summation[Summation:3465562] The soluble form of TNF-α is cleaved from membrane-anchored ...
(hasEvent)[Pathway:75893] TNF signaling [Homo sapiens]
(precedingEvent)[Reaction:83656] TNF:TNFR1 binds TRADD, TRAF2 and RIPK1 [Homo sapiens]
[Reaction:5334740] HPV Suppressed TNF:TNF-R1 binds TRADD, TRAF2 and RIP [Homo sapiens]
[Reaction:5626953] TNF-α:TNFR1 binds DENN/MADD [Homo sapiens]
[Reaction:5626988] TNF-α:TNFR1 binds NSMAF [Homo sapiens]
(updatedInstance)[_UpdateTracker:9784687] Update Tracker - [Reaction:3371353] Soluble TNF-alpha binds TNFR1 - v53:[modifyText]
[_UpdateTracker:9785208] Update Tracker - [Reaction:3371353] Soluble TNF-alpha binds TNFR1 - v52:[addOutput, add_removeInput, modifyText]
[_UpdateTracker:9846957] Update Tracker - [Reaction:3371353] Soluble TNF-α binds TNFR1 - v82:[modifyText]
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