Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person TCF/LEF:CTNNB1:BCL9:PYGO:MLL2:MEN1 complex [nucleoplasm]

Class:IdComplex:3361369
_displayNameTCF/LEF:CTNNB1:BCL9:PYGO:MLL2:MEN1 complex [nucleoplasm]
_timestamp2025-08-29 19:42:59
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:3361371] Rothfels, K, 2013-05-13
hasComponent
isChimericFALSE
literatureReference[LiteratureReference:3322328] The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes
modified[InstanceEdit:3451023] Rothfels, K, 2013-05-16
[InstanceEdit:3451182] Rothfels, K, 2013-05-16
[InstanceEdit:9965461] Orlic-Milacic, Marija, 2025-08-29
[InstanceEdit:9965499] Orlic-Milacic, Marija, 2025-08-29
nameTCF/LEF:CTNNB1:BCL9:PYGO:MLL2:MEN1 complex
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:5646305] R-HSA-3361369.2
(input)[BlackBoxEvent:3364042] APC promotes disassembly of beta-catenin transactivation complex [Homo sapiens]
(output)[Reaction:3364014] Recruitment of MLL2 methyltransferase complex [Homo sapiens]
(physicalEntity)[CatalystActivity:3361372] histone H3K4 methyltransferase activity of TCF/LEF:CTNNB1:BCL9:PYGO:MLL2:MEN1 complex [nucleoplasm]
(updatedInstance)[_UpdateTracker:9972176] Update Tracker - [Complex:3361369] TCF/LEF:CTNNB1:BCL9:PYGO:MLL2:MEN1 complex [nucleoplasm] - v95:[add_removeHasComponent, modifyName]
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No pathways have been reviewed or authored by TCF/LEF:CTNNB1:BCL9:PYGO:MLL2:MEN1 complex [nucleoplasm] (3361369)