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Query author contributions in Reactome

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Details on Person Glutathione peroxidase 1 (GPX1) located in the mitochondrial...

Class:IdSummation:3343737
_displayNameGlutathione peroxidase 1 (GPX1) located in the mitochondrial...
_timestamp2021-03-05 02:29:13
created[InstanceEdit:3343747] May, B, 2013-05-12
literatureReference[LiteratureReference:3323035] Relative contributions of heart mitochondria glutathione peroxidase and catalase to H(2)O(2) detoxification in in vivo conditions
modified[InstanceEdit:3782526] May, B, 2013-06-29
[InstanceEdit:9717163] May, Bruce, 2021-03-05
[InstanceEdit:9717167] May, Bruce, 2021-03-05
textGlutathione peroxidase 1 (GPX1) located in the mitochondrial matrix (Bera et al. 2014) uses glutathione to reduce hydrogen peroxide (H2O2) to yield oxidized glutathione and water (Legault et al. 2000, Li et al. 2000, Faucher et al. 2003, Lu et al. 2012). As inferred from rat mitochondria, GPX1 is the major determinant of steady-state hydrogen peroxide levels (Antunes et al. 2002).
(summation)[Reaction:3323013] GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O [Homo sapiens]
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