Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person HC53,56-P4HB [endoplasmic reticulum lumen]

Class:IdEntityWithAccessionedSequence:3341287
_displayNameHC53,56-P4HB [endoplasmic reticulum lumen]
_timestamp2022-11-07 22:19:08
compartment[Compartment:17957] endoplasmic reticulum lumen
created[InstanceEdit:3341366] May, B, 2013-05-11
endCoordinate508
hasModifiedResidue[IntraChainCrosslinkedResidue:3341345] Intra-chain Crosslink via L-cystine (cross-link) at 53 and 56
modified[InstanceEdit:5653575] May, Bruce, 2014-11-30
[InstanceEdit:9817556] D'Eustachio, Peter, 2022-09-23
[InstanceEdit:9820404] D'Eustachio, Peter, 2022-11-07
nameHC53,56-P4HB
P4HB oxidized
PDIA1
Protein disulfide isomerase
referenceEntity[ReferenceGeneProduct:61444] UniProt:P07237 P4HB [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:5646336] R-HSA-3341287.2
startCoordinate18
(input)[Reaction:264997] P4HB mediates disulfide bond formation in Proinsulin [Homo sapiens]
(output)[Reaction:3341296] GPX7,8 catalyze peroxidation of P4HB (PDI) [Homo sapiens]
[Reaction:9817575] ERO1B oxidizes P4HB [Homo sapiens]
(physicalEntity)[CatalystActivity:265095] protein-disulfide reductase activity of HC53,56-P4HB [endoplasmic reticulum lumen]
(updatedInstance)[_UpdateTracker:9891781] Update Tracker - [EntityWithAccessionedSequence:3341287] HC53,56-P4HB [endoplasmic reticulum lumen] - v52:[addName]
[_UpdateTracker:9905110] Update Tracker - [EntityWithAccessionedSequence:3341287] HC53,56-P4HB [endoplasmic reticulum lumen] - v83:[modifyName]
[Change default viewing format]
No pathways have been reviewed or authored by HC53,56-P4HB [endoplasmic reticulum lumen] (3341287)