Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person Beta-catenin recruits CBP/p300

Class:IdReaction:3322427
_displayNameBeta-catenin recruits CBP/p300
_doReleaseTRUE
_timestamp2015-06-09 18:37:33
authored[InstanceEdit:3640727] Rothfels, K, 2013-05-29
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:3322426] Rothfels, K, 2013-05-03
edited[InstanceEdit:4655138] Gillespie, ME, 2013-10-02
input[Complex:3299548] TCF/LEF:CTNNB1 [nucleoplasm] [Homo sapiens]
[DefinedSet:1027362] CREBBP,EP300 [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:3322349] The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates
[LiteratureReference:3322352] The transcriptional coactivator CBP interacts with beta-catenin to activate gene expression
[LiteratureReference:3322322] Regulation of beta -catenin transformation by the p300 transcriptional coactivator
[LiteratureReference:3322314] Acetylation of beta-catenin by p300 regulates beta-catenin-Tcf4 interaction
[LiteratureReference:3322312] Acetylation of beta-catenin by CREB-binding protein (CBP)
[LiteratureReference:3322350] Wingless signaling induces widespread chromatin remodeling of target loci
modified[InstanceEdit:3774876] Rothfels, K, 2013-06-25
[InstanceEdit:4416357] Rothfels, K, 2013-08-25
[InstanceEdit:4518483] Rothfels, K, 2013-09-03
[InstanceEdit:4655195] Rothfels, K, 2013-10-02
[InstanceEdit:5097343] Rothfels, K, 2013-11-11
[InstanceEdit:5146698] Rothfels, K, 2013-11-18
[InstanceEdit:5251653] Rothfels, K, 2014-02-04
[InstanceEdit:5323634] Rothfels, K, 2014-02-15
[InstanceEdit:5576955] Rothfels, Karen, 2014-05-27
[InstanceEdit:6782938] Rothfels, Karen, 2015-06-09
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameBeta-catenin recruits CBP/p300
output[Complex:3322396] TCF/LEF:CTNNB1:CBP/p300 [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2014-03-12
reviewed[InstanceEdit:5251465] Rajakulendran, Nishani, 2014-01-22
[InstanceEdit:5323527] van Amerongen, R, 2014-02-14
[InstanceEdit:5368564] Kikuchi, Akira, 2014-04-22
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:5644352] R-HSA-3322427.3
summation[Summation:3322316] CBP (CREB-binding protein) and the closely related p300 are ...
(hasEvent)[Pathway:201722] Formation of the beta-catenin:TCF transactivating complex [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by Beta-catenin recruits CBP/p300 (3322427)