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Details on Person Autoglucosylation of GYG2 complexed with GYS2-a

Class:Id	Reaction:3322014
_displayName	Autoglucosylation of GYG2 complexed with GYS2-a
_doRelease	TRUE
_timestamp	2024-12-11 21:03:45
catalystActivity	[CatalystActivity:3322010] glycogenin glucosyltransferase activity of GYG2:GYS2-a tetramer [cytosol]
catalystActivityReference	[CatalystActivityReference:9643816] glycogenin glucosyltransferase activity of GYG2:GYS2-a tetramer [cytosol] Glycogenin-2, a novel self-glucosylating protein involved in liver glycogen biosynthesis
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:3322034] D'Eustachio, P, 2013-05-02
crossReference	[DatabaseIdentifier:9931454] RHEA:23361
input	[SimpleEntity:29410] UDP-Glc [cytosol] [SimpleEntity:29410] UDP-Glc [cytosol] [SimpleEntity:29410] UDP-Glc [cytosol] [SimpleEntity:29410] UDP-Glc [cytosol] [SimpleEntity:29410] UDP-Glc [cytosol] [SimpleEntity:29410] UDP-Glc [cytosol] [SimpleEntity:29410] UDP-Glc [cytosol] [SimpleEntity:29410] UDP-Glc [cytosol] [Complex:3322031] GYG2:GYS2-a tetramer [cytosol] [Homo sapiens]
internalReviewed	[InstanceEdit:9931477] D'Eustachio, Peter, 2024-12-11
literatureReference	[LiteratureReference:70212] Glycogenin-2, a novel self-glucosylating protein involved in liver glycogen biosynthesis [LiteratureReference:3322039] Glycogen and its metabolism: some new developments and old themes
modified	[InstanceEdit:3322069] D'Eustachio, P, 2013-05-02 [InstanceEdit:4006041] D'Eustachio, P, 2013-07-25 [InstanceEdit:4006080] D'Eustachio, P, 2013-07-26 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9931474] D'Eustachio, Peter, 2024-12-11 [InstanceEdit:9931476] D'Eustachio, Peter, 2024-12-11
name	Autoglucosylation of GYG2 complexed with GYS2-a L-tyrosyl-(glycogenin) + UDP-alpha-D-glucose => alpha-D-glucosyl-L-tyrosyl-(glycogenin) + UDP + H(+) 8 UDP-glucose + GYG2 => 8 UDP + oligoGlc-GYG2 (GYS2-a)
output	[SimpleEntity:110096] UDP [cytosol] [SimpleEntity:110096] UDP [cytosol] [SimpleEntity:110096] UDP [cytosol] [SimpleEntity:110096] UDP [cytosol] [SimpleEntity:110096] UDP [cytosol] [SimpleEntity:110096] UDP [cytosol] [SimpleEntity:110096] UDP [cytosol] [SimpleEntity:110096] UDP [cytosol] [Complex:3321999] oligoGlc-GYG2:GYS2-a tetramer [cytosol] [Homo sapiens] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol]
precedingEvent	[Reaction:70286] UTP + D-glucose 1-phosphate => pyrophosphate + UDP-glucose [Homo sapiens] [Reaction:71590] glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] [Homo sapiens] [Reaction:9638127] PGM1:Mg2+ isomerises G6P to G1P [Homo sapiens]
previousReviewStatus	[ReviewStatus:9821384] two stars
releaseDate	2013-09-18
reviewed	[InstanceEdit:4006079] Jassal, B, 2013-07-26
reviewStatus	[ReviewStatus:9821385] four stars
revised	[InstanceEdit:3322070] D'Eustachio, P, 2013-05-02
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:4545320] R-HSA-3322014.5
structureModified	[InstanceEdit:9931474] D'Eustachio, Peter, 2024-12-11
summation	[Summation:3322043] Glycogenin 2 (GYG2) catalyzes its autoglycosylation reaction...
(hasEvent)	[Pathway:3322077] Glycogen synthesis [Homo sapiens]
(precedingEvent)	[Reaction:3322009] GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 [Homo sapiens]
(replacementInstances)	[_Deleted:3698018] Deletion of instance: 70290
(updatedInstance)	[_UpdateTracker:9939824] Update Tracker - [Reaction:3322014] Autoglucosylation of GYG2 complexed with GYS2-a - v92:[removeOutput]
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