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Details on Person KAT7-containing ING4/5 complexes acetylate Me3K-histone H3

Class:Id	Reaction:3318413
_displayName	KAT7-containing ING4/5 complexes acetylate Me3K-histone H3
_doRelease	TRUE
_timestamp	2014-11-20 02:52:30
authored	[InstanceEdit:3214866] Jupe, S, 2013-03-12
catalystActivity	[CatalystActivity:3321838] histone acetyltransferase activity of KAT7:ING4,5 dimers:MEAF6:PHF17,(15,16) [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:3318432] Jupe, S, 2013-04-26
edited	[InstanceEdit:5146786] Jupe, S, 2013-11-18
input	[CandidateSet:4551288] Me3K-histone H3 [nucleoplasm] [Homo sapiens] [SimpleEntity:113560] Ac-CoA [nucleoplasm]
isChimeric	FALSE
literatureReference	[LiteratureReference:3321856] ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation [LiteratureReference:3321862] Molecular basis of histone H3K4me3 recognition by ING4 [LiteratureReference:3321865] The crystal structure of the ING5 PHD finger in complex with an H3K4me3 histone peptide
modified	[InstanceEdit:3321832] Jupe, S, 2013-05-02 [InstanceEdit:4551290] Jupe, S, 2013-09-13 [InstanceEdit:4551304] Jupe, S, 2013-09-13 [InstanceEdit:4568767] Jupe, S, 2013-09-18 [InstanceEdit:4568966] Jupe, S, 2013-09-19 [InstanceEdit:4960919] Jupe, S, 2013-11-04 [InstanceEdit:5144556] Jupe, S, 2013-11-18 [InstanceEdit:5149551] Matthews, L, 2013-11-20 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	KAT7-containing ING4/5 complexes acetylate Me3K-histone H3
output	[CandidateSet:4551287] Ack-Me3K-histone H3 [nucleoplasm] [Homo sapiens] [SimpleEntity:2485002] CoA-SH [nucleoplasm]
releaseDate	2013-12-04
reviewed	[InstanceEdit:5144557] Karagiannis, Tom, 2013-11-18
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5645016] R-HSA-3318413.2
summation	[Summation:3321828] The Inhibitor of Growth (ING) family are growth regulators, ...
(hasEvent)	[Pathway:3214847] HATs acetylate histones [Homo sapiens]
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No pathways have been reviewed or authored by KAT7-containing ING4/5 complexes acetylate Me3K-histone H3 (3318413)