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Details on Person SMAD4 D351H [cytosol]

Class:Id	EntityWithAccessionedSequence:3310965
_displayName	SMAD4 D351H [cytosol]
_timestamp	2013-09-05 12:24:26
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:3310962] Orlic-Milacic, M, 2013-04-24
crossReference	[DatabaseIdentifier:3310968] COSMIC:COSV61684645
disease	[Disease:1500689] cancer [Disease:1248674] large intestine cancer [Disease:1500575] ovarian cancer [Disease:2328198] pancreatic cancer [Disease:1500699] lung cancer
endCoordinate	552
hasModifiedResidue	[ReplacedResidue:3310966] L-aspartic acid 351 replaced with L-histidine
literatureReference	[LiteratureReference:3318202] A structural basis for mutational inactivation of the tumour suppressor Smad4 [LiteratureReference:3304374] SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer
modified	[InstanceEdit:3318205] Orlic-Milacic, M, 2013-04-25
name	SMAD4 D351H SMAD4 Asp351His
referenceEntity	[ReferenceGeneProduct:64628] UniProt:Q13485 SMAD4 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:4545902] R-HSA-3310965.1
startCoordinate	1
(hasMember)	[CandidateSet:3311017] SMAD4 MH2 domain mutants [cytosol] [Homo sapiens]
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No pathways have been reviewed or authored by SMAD4 D351H [cytosol] (3310965)