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Details on Person SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)

Class:IdReaction:3299691
_displayNameSOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)
_doReleaseTRUE
_timestamp2014-11-20 02:46:45
authored[InstanceEdit:3299684] May, B, 2013-04-20
catalystActivity[CatalystActivity:3299693] superoxide dismutase activity of 2xHC-SOD1:Zn2+:Cu2+ dimer [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:3299677] May, B, 2013-04-20
edited[InstanceEdit:3299684] May, B, 2013-04-20
input[SimpleEntity:70106] H+ [cytosol]
[SimpleEntity:70106] H+ [cytosol]
[SimpleEntity:1222424] O2.- [cytosol]
[SimpleEntity:1222424] O2.- [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:3299782] High-level expression of enzymatically active human Cu/Zn superoxide dismutase in Escherichia coli
[LiteratureReference:3299845] Purification of superoxide dismutases from human placenta using immunoadsorbent columns
[LiteratureReference:3299823] Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)
[LiteratureReference:3697046] Does cellular hydrogen peroxide diffuse or act locally?
modified[InstanceEdit:3299848] May, B, 2013-04-21
[InstanceEdit:3343748] May, B, 2013-05-12
[InstanceEdit:3697064] May, B, 2013-06-08
[InstanceEdit:3781825] May, B, 2013-06-28
[InstanceEdit:4415003] May, B, 2013-08-23
[InstanceEdit:4420243] May, B, 2013-08-31
[InstanceEdit:4837349] May, B, 2013-11-01
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameSOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)
output[SimpleEntity:29408] H2O2 [cytosol]
[SimpleEntity:29368] O2 [cytosol]
precedingEvent
releaseDate2013-12-04
reviewed[InstanceEdit:4837339] Kavdia, Mahendra, 2013-11-01
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:5644799] R-HSA-3299691.2
summation[Summation:3299768] Cu-Zn superoxide dismutase (SOD1), originally known as eryth...
(hasEvent)[Pathway:3299685] Detoxification of Reactive Oxygen Species [Homo sapiens]
(precedingEvent)[Reaction:71676] GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O [Homo sapiens]
[Reaction:3341277] GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O [Homo sapiens]
[Reaction:3341343] PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O [Homo sapiens]
[Reaction:3343700] PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O [Homo sapiens]
[Reaction:9861595] Cytosolic H2O2 decarboxylates PYR to acetate [Homo sapiens]
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