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Details on Person MAP3K5 (ASK1) phosphorylates Map2k4(Sek1)

Class:Id	Reaction:3299417
_displayName	MAP3K5 (ASK1) phosphorylates Map2k4(Sek1)
_doRelease	TRUE
_timestamp	2013-09-05 11:52:31
authored	[InstanceEdit:3900006] Orlic-Milacic, M, 2013-07-15
catalystActivity	[CatalystActivity:3228467] protein serine/threonine kinase activity of MAP3K5 [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:3299415] Orlic-Milacic, M, 2013-04-18
edited	[InstanceEdit:3901124] D'Eustachio, P, 2013-07-15 [InstanceEdit:4542306] Matthews, L, 2013-07-15
input	[SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [EntityWithAccessionedSequence:205811] Map2k4 [cytosol] [Mus musculus]
isChimeric	TRUE
literatureReference	[LiteratureReference:3228464] Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
modified	[InstanceEdit:4416364] Orlic-Milacic, M, 2013-08-26 [InstanceEdit:4420304] Orlic-Milacic, M, 2013-09-03 [InstanceEdit:4420306] Orlic-Milacic, M, 2013-09-03 [InstanceEdit:4542311] Orlic-Milacic, M, 2013-09-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	MAP3K5 (ASK1) phosphorylates Map2k4(Sek1)
output	[SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [EntityWithAccessionedSequence:205920] p-S255,T259-Map2k4 [cytosol] [Mus musculus]
releaseDate	2013-09-18
reviewed	[InstanceEdit:4542303] Samarajiwa, Shamith, 2013-09-03
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens [Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:4545324] R-NUL-3299417.2
summation	[Summation:3299416] Recombinant human MAP3K5 (ASK1) is needed for phosphorylatio...
(inferredFrom)	[Reaction:3229152] MAP3K5 (ASK1) phosphorylates MAP2K4 (SEK1) [Homo sapiens]
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