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| Class:Id | Summation:3296494 |
|---|---|
| _displayName | MAP3K5 (ASK1) phosphorylates and activates MAP2K3 (MKK3) and... |
| _timestamp | 2013-07-12 21:00:41 |
| created | [InstanceEdit:3296495] Orlic-Milacic, M, 2013-04-18 |
| modified | [InstanceEdit:3899315] Orlic-Milacic, M, 2013-07-12 |
| text | MAP3K5 (ASK1) phosphorylates and activates MAP2K3 (MKK3) and MAP2K6 (MKK6) (Ichijo et al. 1997). A conserved docking site, DVD, at the C-terminus of MAP2K3 and MAP2K6 is needed for the interaction with MAP3K5 and MAP3K5-mediated activation (Takekawa et al. 2005). |
| (summation) | [Reaction:3228469] MAP3K5 phosphorylates MKK3 and MKK6 [Homo sapiens] |
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