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Details on Person SUMOylation of Fos with SUMO1

Class:Id	Reaction:3261217
_displayName	SUMOylation of Fos with SUMO1
_timestamp	2019-04-08 04:58:00
authored	[InstanceEdit:3247508] May, B, 2013-04-04
catalystActivity	[CatalystActivity:2997650] SUMO transferase activity of SUMO1:C93-UBE2I [nucleoplasm]
catalystActivityReference	[CatalystActivityReference:9644118] SUMO transferase activity of SUMO1:C93-UBE2I [nucleoplasm] Identification of a substrate recognition site on Ubc9
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:3261213] May, B, 2013-04-10
edited	[InstanceEdit:3247508] May, B, 2013-04-04
input	[Complex:3261169] Fos:Jun [nucleoplasm] [Mus musculus] [Complex:2993783] SUMO1:C93-UBE2I [nucleoplasm] [Homo sapiens]
isChimeric	TRUE
literatureReference	[LiteratureReference:3261105] Down-regulation of c-Fos/c-Jun AP-1 dimer activity by sumoylation [LiteratureReference:3261117] SUMOylation of the inducible (c-Fos:c-Jun)/AP-1 transcription complex occurs on target promoters to limit transcriptional activation
modified	[InstanceEdit:3730661] May, B, 2013-06-14 [InstanceEdit:3730900] May, B, 2013-06-16 [InstanceEdit:4663810] May, B, 2013-10-06 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:8936028] May, Bruce, 2016-08-16 [InstanceEdit:8936036] May, Bruce, 2016-08-16 [InstanceEdit:9644119] May, Bruce, 2019-04-08
name	SUMOylation of Fos with SUMO1
output	[Complex:3261161] monoSUMO1-Fos:Jun [nucleoplasm] [Mus musculus] [EntityWithAccessionedSequence:912481] UBE2I [nucleoplasm] [Homo sapiens]
species	[Species:48887] Homo sapiens [Species:48892] Mus musculus [Species:48895] Rattus norvegicus
stableIdentifier	[StableIdentifier:8913711] R-NUL-3261217.1
summation	[Summation:4663758] Fos is sumoylated with Sumo1 at lysine-265 (Bossis et al. 20...
(inferredFrom)	[Reaction:3261209] SUMOylation of FOS with SUMO1 [Homo sapiens]
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No pathways have been reviewed or authored by SUMOylation of Fos with SUMO1 (3261217)