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Details on Person monoSUMO1-K391,477-HIF1A [nucleoplasm]

Class:Id	EntityWithAccessionedSequence:3261177
_displayName	monoSUMO1-K391,477-HIF1A [nucleoplasm]
_timestamp	2022-01-19 16:30:43
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:3261182] May, B, 2013-04-10
endCoordinate	826
hasModifiedResidue	[GroupModifiedResidue:3261160] sumoylated lysine (monoSUMO1 [nucleoplasm]) at 391 [GroupModifiedResidue:3261164] sumoylated lysine (monoSUMO1 [nucleoplasm]) at 477
literatureReference	[LiteratureReference:3261126] Sumoylation increases HIF-1alpha stability and its transcriptional activity [LiteratureReference:3261123] SUMOylation of hypoxia-inducible factor-1alpha reduces its transcriptional activity
modified	[InstanceEdit:3632837] May, B, 2013-05-26 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9762279] May, Bruce, 2022-01-19
name	monoSUMO1-K391,477-HIF1A SUMO1 N-glycyl-lys391,477 HIF1A Hypoxia-inducible factor 1-alpha HIF1A_HUMAN
referenceEntity	[ReferenceGeneProduct:56516] UniProt:Q16665 HIF1A [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8890425] R-HSA-3261177.1
startCoordinate	1
(output)	[Reaction:3296167] PIAS4 SUMOylates HIF1A with SUMO1 [Homo sapiens] [Reaction:5228517] RANBP2 SUMOylates HIF1A with SUMO1 [Homo sapiens]
(replacementInstances)	[_Deleted:9762622] Deletion of instance: 3730740
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No pathways have been reviewed or authored by monoSUMO1-K391,477-HIF1A [nucleoplasm] (3261177)