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Details on Person Activation of STAT6 by STING is critical for antiviral innate immunity
| Class:Id | LiteratureReference:3249356 |
| _displayName | Activation of STAT6 by STING is critical for antiviral innate immunity |
| _timestamp | 2013-04-09 05:46:29 |
| author | [Person:2408410] Chen, Huihui [Person:2453811] Sun, Hui [Person:2408407] You, Fuping [Person:2408406] Sun, Wenxiang [Person:2408408] Zhou, Xiang [Person:2408416] Chen, Lu [Person:3249358] Yang, Jing [Person:3249362] Wang, Yutao [Person:2187397] Tang, H [Person:3249357] Guan, Yukun [Person:3249361] Xia, Weiwei [Person:3249360] Gu, Jun [Person:1834958] Ishikawa, H [Person:3244641] Gutman, Delia [Person:3249355] Barber, Glen [Person:3249359] Qin, Zhihai [Person:2408412] Jiang, Zhengfan |
| created | [InstanceEdit:3249354] Shamovsky, V, 2013-04-09 |
| journal | Cell |
| pages | 436-46 |
| pubMedIdentifier | 22000020 |
| title | Activation of STAT6 by STING is critical for antiviral innate immunity |
| volume | 147 |
| year | 2011 |
| (literatureReference) | [Summation:3249363] Endogenous STAT6 was found to co-fractionate with STING from... [Summation:3249375] Signal transducer and activator of transcription 6 (STAT6) m... [Summation:3261229] Upon viral infection STAT6 undergoes Ser407 phosphorylation,... [Summation:3261233] TBK1 phosphorylates STAT6 on Ser407, which in turn activates... [Summation:3261239] Following tyrosine phosphorylation and dimerization STAT6 tr... [Pathway:3249367] STAT6-mediated induction of chemokines [Homo sapiens] [Reaction:3249370] p-S407,Y641-STAT6 dimer migrates to the nucleus [Homo sapiens] [Reaction:3249371] TBK1 phosphorylates STAT6 at Ser407 [Homo sapiens] [Reaction:3249372] p-S407,Y641-STAT6 is dimerized [Homo sapiens] [Reaction:3249378] STING recruits TBK1 and STAT6 [Homo sapiens] |
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