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Details on Person Activation of STAT6 by STING is critical for antiviral innate immunity

Class:IdLiteratureReference:3249356
_displayNameActivation of STAT6 by STING is critical for antiviral innate immunity
_timestamp2013-04-09 05:46:29
author[Person:2408410] Chen, Huihui
[Person:2453811] Sun, Hui
[Person:2408407] You, Fuping
[Person:2408406] Sun, Wenxiang
[Person:2408408] Zhou, Xiang
[Person:2408416] Chen, Lu
[Person:3249358] Yang, Jing
[Person:3249362] Wang, Yutao
[Person:2187397] Tang, H
[Person:3249357] Guan, Yukun
[Person:3249361] Xia, Weiwei
[Person:3249360] Gu, Jun
[Person:1834958] Ishikawa, H
[Person:3244641] Gutman, Delia
[Person:3249355] Barber, Glen
[Person:3249359] Qin, Zhihai
[Person:2408412] Jiang, Zhengfan
created[InstanceEdit:3249354] Shamovsky, V, 2013-04-09
journalCell
pages436-46
pubMedIdentifier22000020
titleActivation of STAT6 by STING is critical for antiviral innate immunity
volume147
year2011
(literatureReference)[Summation:3249363] Endogenous STAT6 was found to co-fractionate with STING from...
[Summation:3249375] Signal transducer and activator of transcription 6 (STAT6) m...
[Summation:3261229] Upon viral infection STAT6 undergoes Ser407 phosphorylation,...
[Summation:3261233] TBK1 phosphorylates STAT6 on Ser407, which in turn activates...
[Summation:3261239] Following tyrosine phosphorylation and dimerization STAT6 tr...
[Pathway:3249367] STAT6-mediated induction of chemokines [Homo sapiens]
[Reaction:3249370] p-S407,Y641-STAT6 dimer migrates to the nucleus [Homo sapiens]
[Reaction:3249371] TBK1 phosphorylates STAT6 at Ser407 [Homo sapiens]
[Reaction:3249372] p-S407,Y641-STAT6 is dimerized [Homo sapiens]
[Reaction:3249378] STING recruits TBK1 and STAT6 [Homo sapiens]
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No pathways have been reviewed or authored by Activation of STAT6 by STING is critical for antiviral innate immunity (3249356)