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Details on Person The TREX1 double-stranded DNA degradation activity is defective in dominant mutations associated with autoimmune disease

Class:IdLiteratureReference:3247970
_displayNameThe TREX1 double-stranded DNA degradation activity is defective in dominant mutations associated with autoimmune disease
_timestamp2013-04-05 21:36:29
author[Person:3247908] Lehtinen, Duane A
[Person:3244627] Harvey, Scott
[Person:3248016] Mulcahy, Matthew J
[Person:3244615] Hollis, Thomas
[Person:3244652] Perrino, Fred W
created[InstanceEdit:3247941] Shamovsky, V, 2013-04-05
journalJ. Biol. Chem.
pages31649-56
pubMedIdentifier18805785
titleThe TREX1 double-stranded DNA degradation activity is defective in dominant mutations associated with autoimmune disease
volume283
year2008
(literatureReference)[Summation:3247969] TREX1 was shown to bind and degrade the HIV DNA fragments, w...
[Summation:3248005] TREX1 digests unpaired nucleotides on ssDNA and dsDNA ends t...
[Summation:3248010] Three prime repair exonuclease 1 (TREX1) is a DNase type III...
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