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Details on Person PIAS2-1 SUMOylates GTF2IRD1 with SUMO1

Class:Id	Reaction:3246015
_displayName	PIAS2-1 SUMOylates GTF2IRD1 with SUMO1
_timestamp	2022-01-19 16:41:04
authored	[InstanceEdit:3234109] May, B, 2013-03-27
catalystActivity	[CatalystActivity:3246003] SUMO transferase activity of PIAS2-1 [nucleoplasm]
catalystActivityReference	[CatalystActivityReference:9643502] SUMO transferase activity of PIAS2-1 [nucleoplasm] SUMOylation of GTF2IRD1 regulates protein partner interactions and ubiquitin-mediated degradation
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:3246126] May, B, 2013-03-30
edited	[InstanceEdit:3234109] May, B, 2013-03-27
input	[EntityWithAccessionedSequence:3246091] GTF2IRD1 [nucleoplasm] [Homo sapiens] [Complex:2993783] SUMO1:C93-UBE2I [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:3246047] SUMOylation of GTF2IRD1 regulates protein partner interactions and ubiquitin-mediated degradation
modified	[InstanceEdit:3730756] May, B, 2013-06-15 [InstanceEdit:4085380] May, B, 2013-08-05 [InstanceEdit:5187638] May, B, 2013-11-30 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9762281] May, Bruce, 2022-01-19
name	PIAS2-1 SUMOylates GTF2IRD1 with SUMO1
output	[EntityWithAccessionedSequence:912481] UBE2I [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:3246137] monoSUMO1-K495-GTF2IRD1 [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:2993780] Transfer of SUMO1 from E1 to UBE2I (UBC9) [Homo sapiens] [Reaction:2990833] Conjugation of SUMO1 to UBA2:SAE1 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8926583] R-HSA-3246015.1
summation	[Summation:3246122] PIAS2 isoform 1 (PIASx-beta) SUMOylates GTF2IRD1 at lysine-4...
(hasEvent)	[Pathway:3232118] SUMOylation of transcription factors [Homo sapiens]
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No pathways have been reviewed or authored by PIAS2-1 SUMOylates GTF2IRD1 with SUMO1 (3246015)