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Details on Person K27polyUb-NS3 [endoplasmic reticulum membrane]

Class:Id	EntityWithAccessionedSequence:3244645
_displayName	K27polyUb-NS3 [endoplasmic reticulum membrane]
_timestamp	2025-04-18 08:50:32
compartment	[Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:3244632] Shamovsky, V, 2013-03-28
endCoordinate	2093
hasModifiedResidue	[GroupModifiedResidue:9945762] ubiquitinylated lysine (K27polyUb [cytosol]) at unknown position
modified	[InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9920810] Stephan, Ralf, 2024-09-04 [InstanceEdit:9945213] Stephan, Ralf, 2025-04-11 [InstanceEdit:9945736] Stephan, Ralf, 2025-04-17 [InstanceEdit:9945760] Stephan, Ralf, 2025-04-18
name	K27polyUb-NS3 NS3 Serine protease NS3
referenceEntity	[ReferenceGeneProduct:3244616] UniProt:P29990 Unknown [Dengue virus type 2]
species	[Species:3244621] Dengue virus type 2
stableIdentifier	[StableIdentifier:8914108] R-DVI-3244645.1
startCoordinate	1476
(activeUnit)	[CatalystActivity:9922956] helicase activity of DENV m7G(5')pppAm-capped genomic +ssRNA:RC [endoplasmic reticulum membrane] [CatalystActivity:9923984] polynucleotide 5'-phosphatase activity of DENV nascent +ssRNA:RC [endoplasmic reticulum membrane] [CatalystActivity:9925763] helicase activity of DENV -ssRNA genome replicate with secondary dsRNA structure:RC [endoplasmic reticulum membrane]
(hasComponent)	[Complex:3244638] NS2B3 [cytosol] [Dengue virus type 2] [Complex:9918782] NS2B:NS3 [cytosol] [Dengue virus type 2] [Complex:9921209] NS3:NS5 [endoplasmic reticulum membrane] [Dengue virus type 2] [Complex:9921247] NS3:NRBP1 [endoplasmic reticulum membrane] [Homo sapiens] [Complex:9921861] NS3:RIPK1 [endoplasmic reticulum membrane] [Homo sapiens] [Complex:9922172] NS3:HSPA8 [endoplasmic reticulum membrane] [Homo sapiens] [Complex:9948038] NS3:FASN [cytosol] [Homo sapiens] [Complex:9948269] NS3:PDCD6IP [cytosol] [Homo sapiens] [Complex:9979853] NS3:NS5 [endoplasmic reticulum membrane] [Dengue virus type 2]
(input)	[Reaction:9918807] NS2B binds NS3 [Homo sapiens] [Reaction:9920215] NS5 binds NS3 [Homo sapiens] [BlackBoxEvent:9920575] NS3 localizes to the mitochondrial matrix [Homo sapiens] [Reaction:9921263] NS3 binds NRBP1 [Homo sapiens] [Reaction:9921857] NS3 binds RIPK1 [Homo sapiens] [Reaction:9922140] NS3 binds HSPA8 [Homo sapiens] [BlackBoxEvent:9945325] NS3 localizes to nucleus [Homo sapiens] [Reaction:9948053] NS3 binds FASN dimer [Homo sapiens] [Reaction:9948266] NS3 binds PDCD6IP [Homo sapiens]
(output)	[BlackBoxEvent:9945309] NS3 localizes to ER membrane [Homo sapiens] [BlackBoxEvent:9945766] NS3 is ubiquitinated [Homo sapiens]
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No pathways have been reviewed or authored by K27polyUb-NS3 [endoplasmic reticulum membrane] (3244645)