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Details on Person Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA

Class:Id	LiteratureReference:3244591
_displayName	Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA
_timestamp	2013-03-28 05:13:32
author	[Person:3244601] Wu, Jiaxi [Person:2685120] Sun, Lijun [Person:2685308] Chen, Xiang [Person:2984180] Du, Fenghe [Person:3244599] Shi, Heping [Person:3244588] Chen, Chuo [Person:2395999] Chen, Zhijian J
created	[InstanceEdit:3244590] Shamovsky, V, 2013-03-28
journal	Science
pages	826-30
pubMedIdentifier	23258412
title	Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA
volume	339
year	2013
(literatureReference)	[Complex:3244600] STING:cGAMP [cytoplasmic vesicle membrane] [Homo sapiens] [DefinedSet:8982071] cGAS ligands [cytosol] [Human immunodeficiency virus 1] [Reaction:3244614] cGAS produces cyclic GMP-AMP [Homo sapiens] [BlackBoxEvent:3244643] STING binds cyclic GMP-AMP [Homo sapiens] [CatalystActivityReference:9643596] cyclic-GMP-AMP synthase activity of cGAS:dsDNA [cytosol] Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA [Summation:3249345] Direct binding assays with radiolabeled substrate showed tha... [Summation:3249351] Cyclic dinucleotides (such as c-di-GMP and c-di-AMP) are sig...
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