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Details on Person EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

Class:IdLiteratureReference:3240776
_displayNameEZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer
_timestamp2013-03-27 20:18:20
author[Person:3229101] Bracken, Adrian P
[Person:3211733] Pasini, Diego
[Person:3240775] Capra, Maria
[Person:3222586] Prosperini, Elena
[Person:3240772] Colli, Elena
[Person:3211694] Helin, Kristian
created[InstanceEdit:3240780] Orlic-Milacic, M, 2013-03-27
journalEMBO J.
pages5323-35
pubMedIdentifier14532106
titleEZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer
volume22
year2003
(literatureReference)[Complex:3240767] EED Gene:E2F1/2/3:DP1/2 [nucleoplasm] [Homo sapiens]
[Complex:3240771] EZH2 Gene:E2F1/2/3:DP1/2 [nucleoplasm] [Homo sapiens]
[RegulationReference:9641486] Positive gene expression regulation by 'EZH2 Gene:E2F1/2/3:DP1/2 [nucleoplasm]' EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer
[RegulationReference:9641576] Positive gene expression regulation by 'EED Gene:E2F1/2/3:DP1/2 [nucleoplasm]' EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer
[Pathway:2559580] Oxidative Stress Induced Senescence [Homo sapiens]
[Reaction:3240765] E2F1/2/3:DP1/2 binds EED gene promoter [Homo sapiens]
[Reaction:3240777] E2F1/2/3:DP1/2 binds EZH2 gene promoter [Homo sapiens]
[BlackBoxEvent:3240782] E2F1/2/3 stimulates EED transcription [Homo sapiens]
[BlackBoxEvent:3240783] E2F1/2/3 stimulates EZH2 transcription [Homo sapiens]
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