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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person DOT1L [nucleoplasm]

Class:IdEntityWithAccessionedSequence:3239030
_displayNameDOT1L [nucleoplasm]
_timestamp2023-10-31 23:23:47
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:3239028] Jupe, S, 2013-03-27
endCoordinate1537
modified[InstanceEdit:9851828] D'Eustachio, Peter, 2023-10-31
nameDOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific
DOT1L_HUMAN
KMT4
referenceEntity[ReferenceGeneProduct:53814] UniProt:Q8TEK3 DOT1L [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:5681075] R-HSA-3239030.2
startCoordinate1
(hasComponent)[Complex:9036507] DOT1L:MLLT3:SCNN1A gene [nucleoplasm] [Homo sapiens]
(hasMember)[CandidateSet:1183246] Histone-lysine methyltransferases [nucleoplasm] [Homo sapiens]
(input)[Reaction:9036525] DOT1L, MLLT3 bind the SCNN1A gene [Homo sapiens]
(output)[BlackBoxEvent:9036446] Expression of DOT1L regulated by NR3C2 [Homo sapiens]
(physicalEntity)[CatalystActivity:5649792] histone H3 methyltransferase activity of DOT1L [nucleoplasm]
(updatedInstance)[_UpdateTracker:9906532] Update Tracker - [EntityWithAccessionedSequence:3239030] DOT1L [nucleoplasm] - v87:[modifyEndCoordinate]
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No pathways have been reviewed or authored by DOT1L [nucleoplasm] (3239030)