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Details on Person CALM1:Ca2+ binds CNG channel

Class:IdReaction:3229181
_displayNameCALM1:Ca2+ binds CNG channel
_doReleaseTRUE
_timestamp2015-09-04 10:59:26
authored[InstanceEdit:3229194] Jassal, Bijay, 2013-03-26
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:3229194] Jassal, Bijay, 2013-03-26
edited[InstanceEdit:3229194] Jassal, Bijay, 2013-03-26
input[Complex:74294] CALM1:4xCa2+ [cytosol] [Homo sapiens]
[Complex:74001] CNG channel [plasma membrane] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:74025] Subunit 2 (or beta) of retinal rod cGMP-gated cation channel is a component of the 240-kDa channel-associated protein and mediates Ca(2+)-calmodulin modulation.
[LiteratureReference:74024] Modulation of the cGMP-gated channel of rod photoreceptor cells by calmodulin.
[LiteratureReference:3262459] Interaction of calmodulin with the cyclic GMP-gated channel of rod photoreceptor cells. Modulation of activity, affinity purification, and localization
modified[InstanceEdit:3262437] Jassal, Bijay, 2013-04-10
[InstanceEdit:3270611] Jassal, Bijay, 2013-04-11
[InstanceEdit:3632877] Jassal, Bijay, 2013-05-28
[InstanceEdit:6793944] Jassal, Bijay, 2015-09-04
[InstanceEdit:9606200] Wu, G, 2018-04-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameCALM1:Ca2+ binds CNG channel
Calmodulin:Ca2+ lowers CNG channel sensitivity to cGMP
output[Complex:3229184] CALM1:Ca2+:CNG channel [plasma membrane] [Homo sapiens]
regulatedBy[PositiveRegulation:3229230] Positive regulation by 'Ca2+ [cytosol]'
releaseDate2013-06-11
reviewed[InstanceEdit:3270610] Makino, C, 2013-04-11
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:3654457] R-HSA-3229181.4
summation[Summation:3229202] As the channels reopen, rising Ca2+ levels result in binding...
(hasEvent)[Pathway:2514859] Inactivation, recovery and regulation of the phototransduction cascade [Homo sapiens]
(updatedInstance)[_UpdateTracker:9783939] Update Tracker - [Reaction:3229181] CALM1:Ca2+ binds CNG channel - v55:[add_removeInput]
[_UpdateTracker:9786727] Update Tracker - [Reaction:3229181] CALM1:Ca2+ binds CNG channel - v48:[add_removeRegulator]
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No pathways have been reviewed or authored by CALM1:Ca2+ binds CNG channel (3229181)