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Details on Person Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS
| Class:Id | LiteratureReference:3222577 |
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| _displayName | Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS |
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| _timestamp | 2013-03-23 10:26:26 |
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| author | [Person:3222565] Barradas, Marta
[Person:3222578] Anderton, Emma
[Person:3222580] Acosta, Juan Carlos
[Person:3222569] Li, Side
[Person:3222576] Banito, Ana
[Person:3222579] Rodriguez-Niedenführ, Marc
[Person:3222566] Maertens, Goedele
[Person:3222575] Banck, Michaela
[Person:3222573] Zhou, Ming-Ming
[Person:3222568] Walsh, Martin J
[Person:3222574] Peters, Gordon
[Person:3222571] Gil, Jesús |
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| created | [InstanceEdit:3222572] Orlic-Milacic, M, 2013-03-23 |
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| journal | Genes Dev. |
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| pages | 1177-82 |
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| pubMedIdentifier | 19451218 |
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| title | Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS |
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| volume | 23 |
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| year | 2009 |
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| (literatureReference) | [Pathway:2559580] Oxidative Stress Induced Senescence [Homo sapiens]
[Reaction:3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter [Homo sapiens]
[BlackBoxEvent:3223200] Demethylation of H3K27Me3 by KDM6B stimulates p16INK4A transcription, while binding of PRC1.4 complex to H3K27Me3 represses p16INK4A transcription [Homo sapiens]
[RegulationReference:9642580] Positive regulation by 'KDM6B:Fe2+ [nucleoplasm]' The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing
[Complex:3222570] CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] [Homo sapiens] |
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