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Details on Person AP-1 complex stimulates KDM6B transcription

Class:Id	BlackBoxEvent:3222546
_displayName	AP-1 complex stimulates KDM6B transcription
_doRelease	TRUE
_timestamp	2017-02-21 16:25:55
authored	[InstanceEdit:3900006] Orlic-Milacic, M, 2013-07-15
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:3222547] Orlic-Milacic, M, 2013-03-22
edited	[InstanceEdit:3901124] D'Eustachio, P, 2013-07-15 [InstanceEdit:4542306] Matthews, L, 2013-07-15
input	[EntityWithAccessionedSequence:3222526] KDM6B Gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:3222540] Loss of the candidate tumor suppressor BTG3 triggers acute cellular senescence via the ERK-JMJD3-p16(INK4a) signaling axis
modified	[InstanceEdit:3222581] Orlic-Milacic, M, 2013-03-23 [InstanceEdit:3223203] Orlic-Milacic, M, 2013-03-25 [InstanceEdit:3296496] Orlic-Milacic, M, 2013-04-18 [InstanceEdit:3772124] Orlic-Milacic, M, 2013-06-24 [InstanceEdit:3772125] Orlic-Milacic, M, 2013-06-24 [InstanceEdit:3779452] Orlic-Milacic, M, 2013-06-27 [InstanceEdit:4415004] Orlic-Milacic, M, 2013-08-23 [InstanceEdit:4416362] Orlic-Milacic, M, 2013-08-26 [InstanceEdit:4420297] Orlic-Milacic, M, 2013-09-03 [InstanceEdit:4542310] Orlic-Milacic, M, 2013-09-04 [InstanceEdit:8979073] Orlic-Milacic, Marija, 2017-02-21 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	AP-1 complex stimulates KDM6B transcription
output	[EntityWithAccessionedSequence:1629833] KDM6B [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:3222533] ERK1/2-activated AP1 complex binds KDM6B promoter [Homo sapiens] [Reaction:450292] Formation of Activated Protein 1 (AP-1) complex. cFOS/c-JUN heterodimer. [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:3222567] Positive gene expression regulation by 'p-2S-cJUN:p-2S,2T-cFOS:KDM6B Gene [nucleoplasm]'
regulationReference	[RegulationReference:9641815] Positive gene expression regulation by 'p-2S-cJUN:p-2S,2T-cFOS:KDM6B Gene [nucleoplasm]' Loss of the candidate tumor suppressor BTG3 triggers acute cellular senescence via the ERK-JMJD3-p16(INK4a) signaling axis
releaseDate	2013-09-18
reviewed	[InstanceEdit:4542303] Samarajiwa, Shamith, 2013-09-03
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:4545348] R-HSA-3222546.5
summation	[Summation:3772123] Binding of the AP-1 (JUN:FOS) subunit JUN to the KDM6B (JMJD...
(hasEvent)	[Pathway:2559580] Oxidative Stress Induced Senescence [Homo sapiens]
(precedingEvent)	[Reaction:8979071] KDM6B binds iron [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9781746] Update Tracker - [BlackBoxEvent:3222546] AP-1 complex stimulates KDM6B transcription - v60:[add_removeOutput]
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No pathways have been reviewed or authored by AP-1 complex stimulates KDM6B transcription (3222546)