Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77

Class:Id	Reaction:3215385
_displayName	CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77
_doRelease	TRUE
_timestamp	2014-11-20 02:35:24
authored	[InstanceEdit:3214866] Jupe, S, 2013-03-12
catalystActivity	[CatalystActivity:5205606] cyclin-dependent protein serine/threonine kinase regulator activity of CCND1:CDK4:PRMT5:WDR77 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:3215411] Jupe, S, 2013-03-15
edited	[InstanceEdit:3215411] Jupe, S, 2013-03-15
input	[Complex:5205612] CCND1:CDK4:PRMT5:WDR77 [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:3215459] Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase
modified	[InstanceEdit:4717428] Jupe, S, 2013-10-17 [InstanceEdit:5084126] Jupe, S, 2013-11-08 [InstanceEdit:5205613] Jupe, S, 2013-12-04 [InstanceEdit:5205795] Jupe, S, 2013-12-06 [InstanceEdit:5250186] Jupe, S, 2014-01-23 [InstanceEdit:5423532] Jupe, Steve, 2014-05-09 [InstanceEdit:5612461] Jupe, Steve, 2014-07-23 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77
output	[Complex:5205604] CCND1:CDK4:PRMT5:pT5-WDR77 [nucleoplasm] [Homo sapiens]
releaseDate	2014-06-10
reviewed	[InstanceEdit:5423560] Guccione, Ernesto, 2014-05-09 [InstanceEdit:5612458] Fischle, Wolfgang, 2014-07-23
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5644370] R-HSA-3215385.2
summation	[Summation:3215429] Phosphorylation of WDR77 (MEP50) on threonine-5 by cyclin-de...
(hasEvent)	[Pathway:3214858] RMTs methylate histone arginines [Homo sapiens]
(precedingEvent)	[Reaction:3215426] COPRS binds CCND1:CDK4:PRMT5:pT5-WDR77 [Homo sapiens] [Reaction:5205799] CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) [Homo sapiens] [Reaction:5661117] CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9785955] Update Tracker - [Reaction:3215385] CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77 - v50:[modifyText]
[Change default viewing format]

No pathways have been reviewed or authored by CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77 (3215385)