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Details on Person KDM1A, KDM1B demethylate MeK5-histone H3

Class:Id	Reaction:3214912
_displayName	KDM1A, KDM1B demethylate MeK5-histone H3
_doRelease	TRUE
_timestamp	2015-03-04 04:00:25
authored	[InstanceEdit:3214866] Jupe, S, 2013-03-12
catalystActivity	[CatalystActivity:4687004] histone demethylase activity of KDM1A,KDM1B [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:3214908] Jupe, S, 2013-03-13
edited	[InstanceEdit:5252136] Jupe, S, 2014-02-05
input	[CandidateSet:5173296] MeK5-histone H3 [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:3214909] Histone demethylation mediated by the nuclear amine oxidase homolog LSD1 [LiteratureReference:5423034] KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints
modified	[InstanceEdit:4687018] Jupe, S, 2013-10-15 [InstanceEdit:4687055] Jupe, S, 2013-10-16 [InstanceEdit:4722136] Jupe, S, 2013-10-22 [InstanceEdit:4755541] Jupe, S, 2013-10-25 [InstanceEdit:5084126] Jupe, S, 2013-11-08 [InstanceEdit:5263691] Jupe, S, 2014-02-14 [InstanceEdit:5334721] Matthews, Lisa, 2014-02-25 [InstanceEdit:5423073] Jupe, Steve, 2014-05-08 [InstanceEdit:5661119] Jupe, Steve, 2015-01-09 [InstanceEdit:5674563] Jupe, Steve, 2015-02-13 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	KDM1A, KDM1B demethylate MeK5-histone H3
output	[CandidateSet:4657030] Histone H3 [nucleoplasm] [Homo sapiens] [SimpleEntity:29478] CH2O [nucleoplasm]
releaseDate	2014-06-10
reviewed	[InstanceEdit:5423120] Schofield, Christopher J, 2014-05-08 [InstanceEdit:5423100] Walport, Louise, 2014-05-08 [InstanceEdit:5423113] Hopkinson, Richard, 2014-05-08
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5644707] R-HSA-3214912.2
summation	[Summation:3214906] Histone demethylases (HDMs) belong to two groups with distin...
(hasEvent)	[Pathway:3214842] HDMs demethylate histones [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9785109] Update Tracker - [Reaction:3214912] KDM1A, KDM1B demethylate MeK5-histone H3 - v52:[add_removeInput, add_removeOutput]
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No pathways have been reviewed or authored by KDM1A, KDM1B demethylate MeK5-histone H3 (3214912)