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Details on Person TP53 Tetramer [nucleoplasm]

Class:Id	Complex:3209194
_displayName	TP53 Tetramer [nucleoplasm]
_timestamp	2013-09-05 12:26:43
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:3209187] Orlic-Milacic, M, 2013-03-01
hasComponent	[EntityWithAccessionedSequence:69488] TP53 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:69488] TP53 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:69488] TP53 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:69488] TP53 [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
name	TP53 Tetramer
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:4545950] R-HSA-3209194.1
(activeUnit)	[PositiveGeneExpressionRegulation:5628903] Positive gene expression regulation by 'TP53 Tetramer:TIGAR Gene [nucleoplasm]' [PositiveRegulation:5629192] Positive regulation by 'TP53 Tetramer:SESN1,2,3 Genes [nucleoplasm]' [PositiveGeneExpressionRegulation:5632769] Positive gene expression regulation by 'TP53 Tetramer:SCO2 Gene [nucleoplasm]' [PositiveGeneExpressionRegulation:5632893] Positive gene expression regulation by 'TP53 Tetramer:RRM2B Gene [nucleoplasm]' [PositiveGeneExpressionRegulation:5632932] Positive gene expression regulation by 'TP53 Tetramer:GLS2 Gene [nucleoplasm]' [PositiveGeneExpressionRegulation:5632990] Positive gene expression regulation by 'TP53 Tetramer:PTEN Gene [nucleoplasm]' [PositiveGeneExpressionRegulation:6792488] Positive gene expression regulation by 'TP53 Tetramer:CCNG1 Gene [nucleoplasm]' [PositiveGeneExpressionRegulation:8944185] Positive gene expression regulation by 'TP53 Tetramer:PTEN Gene [nucleoplasm]' [NegativeGeneExpressionRegulation:9959870] Negative gene expression regulation by 'TP53 tetramer:ARG1 gene [nucleoplasm]' [NegativeGeneExpressionRegulation:9959873] Negative gene expression regulation by 'TP53 tetramer:CPS1 gene [nucleoplasm]' List all 11 refering instances
(hasCandidate)	[CandidateSet:5632387] TP63 Tetramer/ TP53 Tetramer [nucleoplasm] [Homo sapiens]
(hasComponent)	[Complex:69489] MDM2:TP53 [nucleoplasm] [Homo sapiens] [Complex:992690] Myb:SIN3A:p53 [nucleoplasm] [Homo sapiens] [Complex:992748] p53:MYB:SIN3A [nucleoplasm] [Homo sapiens] [Complex:3215173] ING3:TP53 [nucleoplasm] [Homo sapiens] [Complex:3215180] ING5:TP53 [nucleoplasm] [Homo sapiens] [Complex:3215183] ING1:TP53 [nucleoplasm] [Homo sapiens] [Complex:3215190] ING4:TP53 [nucleoplasm] [Homo sapiens] [Complex:3221608] CHD8:Histone H1:TP53 [nucleoplasm] [Homo sapiens] [Complex:3221962] TP53:ARMC10-2 [nucleoplasm] [Homo sapiens] [Complex:3221977] TP53:BANP [nucleoplasm] [Homo sapiens] List all 28 refering instances
(input)	[Reaction:69684] Phosphorylation of p53 by ATM-activated Chk1 [Homo sapiens] [Reaction:992696] p53, SIN3A and MYB form a complex [Homo sapiens] [Reaction:992753] p53 and Sin3a bind c-Myb [Homo sapiens] [Reaction:3215221] ING proteins bind TP53 [Homo sapiens] [Reaction:3221600] CHD8 binds TP53 and histone H1 [Homo sapiens] [Reaction:3221964] ARMC10-2 binda TP53 [Homo sapiens] [Reaction:3221982] BANP binds TP53 [Homo sapiens] [Reaction:3221998] CDKN2AIP binds TP53 [Homo sapiens] [Reaction:3222037] E4F1 binds TP53 [Homo sapiens] [Reaction:3222062] FBXO42:SKP1:CUL1:RBX1 ubiquitinates TP53 [Homo sapiens] List all 38 refering instances
(output)	[Reaction:3215310] USP7 deubiquitinates TP53 and counteracts MDM2 [Homo sapiens] [Reaction:3222212] USP10 deubiquitinates T53 [Homo sapiens] [Reaction:6804762] TP53 forms homotetramers [Homo sapiens] [Reaction:6804996] p14ARF sequesters MDM2 [Homo sapiens]
(physicalEntity)	[CatalystActivity:9988056] DNA-binding transcription repressor activity of TP53 Tetramer [nucleoplasm]
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No pathways have been reviewed or authored by TP53 Tetramer [nucleoplasm] (3209194)