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Details on Person ERF inhibits ETS2 expression

Class:Id	BlackBoxEvent:3209179
_displayName	ERF inhibits ETS2 expression
_doRelease	TRUE
_timestamp	2017-08-02 12:55:14
authored	[InstanceEdit:3900006] Orlic-Milacic, M, 2013-07-15
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:3209180] Orlic-Milacic, M, 2013-03-01
edited	[InstanceEdit:3901124] D'Eustachio, P, 2013-07-15 [InstanceEdit:4542306] Matthews, L, 2013-07-15
input	[EntityWithAccessionedSequence:3209178] ETS2 Gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:3209175] ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation
modified	[InstanceEdit:3245936] Orlic-Milacic, M, 2013-03-28 [InstanceEdit:3295586] Orlic-Milacic, M, 2013-04-17 [InstanceEdit:3779453] Orlic-Milacic, M, 2013-06-27 [InstanceEdit:4415004] Orlic-Milacic, M, 2013-08-23 [InstanceEdit:4420304] Orlic-Milacic, M, 2013-09-03 [InstanceEdit:4420306] Orlic-Milacic, M, 2013-09-03 [InstanceEdit:4542310] Orlic-Milacic, M, 2013-09-04 [InstanceEdit:9014584] Orlic-Milacic, Marija, 2017-08-02 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ERF inhibits ETS2 expression
output	[EntityWithAccessionedSequence:1629811] ETS2 [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:3209177] ERF binds ETS2 promoter [Homo sapiens]
regulatedBy	[NegativeGeneExpressionRegulation:3209181] Negative gene expression regulation by 'ERF:ETS2 Gene [nucleoplasm]'
regulationReference	[RegulationReference:9642650] Negative gene expression regulation by 'ERF:ETS2 Gene [nucleoplasm]' ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation
releaseDate	2013-09-18
reviewed	[InstanceEdit:4542303] Samarajiwa, Shamith, 2013-09-03
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:4545086] R-HSA-3209179.5
summation	[Summation:3245933] Binding of ERF to ETS2 promoter strongly represses ETS2 tran...
(hasEvent)	[Pathway:2559585] Oncogene Induced Senescence [Homo sapiens]
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No pathways have been reviewed or authored by ERF inhibits ETS2 expression (3209179)