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Details on Person Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence

Class:IdLiteratureReference:3200021
_displayNameOpposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence
_timestamp2013-02-27 22:23:26
author[Person:3200024] Ohtani, N
[Person:3200025] Zebedee, Z
[Person:3200022] Huot, T J
[Person:3200019] Stinson, J A
[Person:3200027] Sugimoto, M
[Person:3200028] Ohashi, Y
[Person:3200031] Sharrocks, A D
[Person:3200030] Peters, G
[Person:3200020] Hara, E
created[InstanceEdit:3200026] Orlic-Milacic, M, 2013-02-27
journalNature
pages1067-70
pubMedIdentifier11234019
titleOpposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence
volume409
year2001
(literatureReference)[RegulationReference:9641357] Negative regulation by 'p-T72-ETS2:ID1 [nucleoplasm]' Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence
[RegulationReference:9641721] Positive gene expression regulation by 'p-T38-ETS1/ p-T72-ETS2:CDKN2A Gene [nucleoplasm]' Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence
[Summation:3209103] ETS1 and ETS2, activated by RAS/RAF/MAP kinase cascade, bind...
[Pathway:2559585] Oncogene Induced Senescence [Homo sapiens]
[Reaction:3200023] Phosphorylated ETS1 binds p16INK4A promoter [Homo sapiens]
[BlackBoxEvent:3209098] p-T38-ETS1/p-T72-ETS2 stimulates transcription of p16INK4A mRNA [Homo sapiens]
[Reaction:3209165] ID1 sequesters ETS2 [Homo sapiens]
[Reaction:8979082] Phosphorylated ETS2 binds p16INK4A promoter [Homo sapiens]
[Complex:3209172] p-T72-ETS2:ID1 [nucleoplasm] [Homo sapiens]
[Complex:8979081] p-T72-ETS2:CDKN2A gene [nucleoplasm] [Homo sapiens]
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