Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person MMAB adenosylates cob(I)alamin

Class:Id	Reaction:3159253
_displayName	MMAB adenosylates cob(I)alamin
_doRelease	TRUE
_timestamp	2022-02-10 19:36:15
authored	[InstanceEdit:196747] Jassal, B, 2007-04-24 08:38:46
catalystActivity	[CatalystActivity:3159301] corrinoid adenosyltransferase activity of 3xMMAB [mitochondrial matrix]
catalystActivityReference	[CatalystActivityReference:9759577] cob(I)yrinic acid a,c-diamide adenosyltransferase activity of 3xMMAB [mitochondrial matrix] Redox-Linked Coordination Chemistry Directs Vitamin B₁₂ Trafficking
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:3159299] Jassal, Bijay, 2013-02-20
edited	[InstanceEdit:3159299] Jassal, Bijay, 2013-02-20
input	[SimpleEntity:113593] ATP [mitochondrial matrix] [SimpleEntity:113593] ATP [mitochondrial matrix] [SimpleEntity:3149564] cob(II)alamin [mitochondrial matrix] [SimpleEntity:3149564] cob(II)alamin [mitochondrial matrix] [SimpleEntity:31649] FADH2 [mitochondrial matrix]
isChimeric	FALSE
literatureReference	[LiteratureReference:9758714] Redox-Linked Coordination Chemistry Directs Vitamin B₁₂ Trafficking [LiteratureReference:9759565] Sacrificial Cobalt-Carbon Bond Homolysis in Coenzyme B₁₂ as a Cofactor Conservation Strategy [LiteratureReference:3159257] Functional characterization and mutation analysis of human ATP:Cob(I)alamin adenosyltransferase [LiteratureReference:3159291] Identification of the gene responsible for the cblA complementation group of vitamin B12-responsive methylmalonic acidemia based on analysis of prokaryotic gene arrangements [LiteratureReference:3159296] Identification of the human and bovine ATP:Cob(I)alamin adenosyltransferase cDNAs based on complementation of a bacterial mutant [LiteratureReference:9759571] Spectroscopic evidence for the formation of a four-coordinate Co2+ cobalamin species upon binding to the human ATP:cobalamin adenosyltransferase
modified	[InstanceEdit:3162927] Jassal, Bijay, 2013-02-21 [InstanceEdit:3162930] Jassal, Bijay, 2013-02-21 [InstanceEdit:3288226] Jassal, Bijay, 2013-04-15 [InstanceEdit:3322153] Jassal, Bijay, 2013-05-03 [InstanceEdit:3928680] Jassal, Bijay, 2013-07-23 [InstanceEdit:9759580] D'Eustachio, Peter, 2021-12-07 [InstanceEdit:9760391] D'Eustachio, Peter, 2021-12-17 [InstanceEdit:9764259] D'Eustachio, Peter, 2022-02-10 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	MMAB adenosylates cob(I)alamin 2 ATP + 2 cob(II)alamin + reduced (electron-transfer flavoprotein) => 2 adenosylcob(III)alamin + 3 H(+) + oxidized (electron-transfer flavoprotein) + 2 triphosphate
output	[SimpleEntity:3159274] PPP [mitochondrial matrix] [SimpleEntity:3159274] PPP [mitochondrial matrix] [SimpleEntity:3159297] AdoCbl [mitochondrial matrix] [SimpleEntity:3159297] AdoCbl [mitochondrial matrix] [SimpleEntity:113529] H+ [mitochondrial matrix] [SimpleEntity:113529] H+ [mitochondrial matrix] [SimpleEntity:113529] H+ [mitochondrial matrix] [SimpleEntity:113596] FAD [mitochondrial matrix]
precedingEvent	[Reaction:3149563] MMADHC targets transport of cytosolic cob(II)alamin to mitochondria [Homo sapiens] [Reaction:3149494] MMACHC:cob(II)alamin binds MMADHC [Homo sapiens]
releaseDate	2013-06-11
reviewed	[InstanceEdit:3288227] D'Eustachio, P, 2013-04-15
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:3654468] R-HSA-3159253.3
summation	[Summation:3162925] In a complex reaction, MMAB (mitochondrial cob(I)yrinic acid...
(hasEvent)	[Pathway:9759218] Cobalamin (Cbl) metabolism [Homo sapiens]
(normalReaction)	[FailedReaction:3322125] Defective MMAB does not transfer adenosyl group from ATP to B12s [Homo sapiens]
(precedingEvent)	[Reaction:3159259] MMAA:MUT binds AdoCbl [Homo sapiens]
(replacementInstances)	[_Deleted:9759584] Deletion of instance: 3149560
(updatedInstance)	[_UpdateTracker:9775118] Update Tracker - [Reaction:3159253] MMAB adenosylates cob(I)alamin - v80:[addLiteratureReference, addOutput, add_removeInput, modifyText] [_UpdateTracker:9786322] Update Tracker - [Reaction:3159253] MMAB adenosylates cob(I)alamin - v50:[modifyText] [_UpdateTracker:9787135] Update Tracker - [Reaction:3159253] MMAB adenosylates cob(I)alamin - v46:[modifyText]
[Change default viewing format]

No pathways have been reviewed or authored by MMAB adenosylates cob(I)alamin (3159253)