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Details on Person LRR FLII-interacting protein 1 binds dsDNA

Class:IdReaction:3134896
_displayNameLRR FLII-interacting protein 1 binds dsDNA
_doReleaseTRUE
_timestamp2017-07-26 05:36:40
authored[InstanceEdit:3065946] Shamovsky, V, 2013-02-06
compartment[Compartment:70101] cytosol
created[InstanceEdit:3134899] Shamovsky, V, 2013-02-13
edited[InstanceEdit:3465604] Shamovsky, V, 2013-05-17
input[Complex:3134884] LRR FLII-interacting protein 1 dimer [cytosol] [Homo sapiens]
[GenomeEncodedEntity:9013817] HCV dsDNA [cytosol] [Hepatitis C Virus]
isChimericFALSE
literatureReference[LiteratureReference:3134932] Crystal structure of the dimeric coiled-coil domain of the cytosolic nucleic acid sensor LRRFIP1
[LiteratureReference:3134936] The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway
modified[InstanceEdit:3249352] Shamovsky, V, 2013-04-08
[InstanceEdit:3465583] Shamovsky, V, 2013-05-17
[InstanceEdit:3465600] Shamovsky, V, 2013-05-17
[InstanceEdit:3465604] Shamovsky, V, 2013-05-17
[InstanceEdit:3597629] Shamovsky, V, 2013-05-21
[InstanceEdit:9013818] Shamovsky, Veronica, 2017-07-26
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameLRR FLII-interacting protein 1 binds dsDNA
output[Complex:3134917] dsDNA:LRR FLII-interacting protein 1dimer [cytosol] [Homo sapiens]
relatedSpecies[Species:5621375] Hepatitis C Virus
releaseDate2013-06-11
reviewed[InstanceEdit:3110284] D'Eustachio, P, 2013-02-11
[InstanceEdit:3597627] Jin, Lei, 2013-05-21
[InstanceEdit:3597624] Wu, Jiaxi, 2013-05-21
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:3654459] R-HSA-3134896.3
summation[Summation:3134916] LRRFIP1 can recognize both AT-rich B-form dsDNA and GC-rich ...
(hasEvent)[Pathway:3134973] LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production [Homo sapiens]
(precedingEvent)[Reaction:3134901] LRR FLII-interacting protein 1 associates with beta-catenin [Homo sapiens]
(updatedInstance)[_UpdateTracker:9780627] Update Tracker - [Reaction:3134896] LRR FLII-interacting protein 1 binds dsDNA - v62:[add_removeInput, modifyText]
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No pathways have been reviewed or authored by LRR FLII-interacting protein 1 binds dsDNA (3134896)