Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person DNA-PK binds microbial dsDNA

Class:IdReaction:3134821
_displayNameDNA-PK binds microbial dsDNA
_doReleaseTRUE
_timestamp2017-07-26 05:28:54
authored[InstanceEdit:3065946] Shamovsky, V, 2013-02-06
compartment[Compartment:70101] cytosol
created[InstanceEdit:3134846] Shamovsky, V, 2013-02-13
edited[InstanceEdit:3465604] Shamovsky, V, 2013-05-17
input[EntityWithAccessionedSequence:3134816] PRKDC [cytosol] [Homo sapiens]
[Complex:3134809] Ku70:Ku80 heterodimer [cytosol] [Homo sapiens]
[DefinedSet:9013760] DNA-PK ligands [cytosol] [Vaccinia virus]
isChimericFALSE
literatureReference[LiteratureReference:3134806] DNA-PK is a DNA sensor for IRF-3-dependent innate immunity
[LiteratureReference:3134836] Cutting edge: Ku70 is a novel cytosolic DNA sensor that induces type III rather than type I IFN
modified[InstanceEdit:3134964] Shamovsky, V, 2013-02-13
[InstanceEdit:3222295] Shamovsky, V, 2013-03-18
[InstanceEdit:3249352] Shamovsky, V, 2013-04-08
[InstanceEdit:3465583] Shamovsky, V, 2013-05-17
[InstanceEdit:3465600] Shamovsky, V, 2013-05-17
[InstanceEdit:3465604] Shamovsky, V, 2013-05-17
[InstanceEdit:3597629] Shamovsky, V, 2013-05-21
[InstanceEdit:9013762] Shamovsky, Veronica, 2017-07-26
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameDNA-PK binds microbial dsDNA
output[Complex:3134811] DNA-PK:microbial dsDNA [cytosol] [Homo sapiens]
relatedSpecies[Species:5229092] Hepatitis B virus
[Species:2671785] Vaccinia virus
releaseDate2013-06-11
reviewed[InstanceEdit:3110284] D'Eustachio, P, 2013-02-11
[InstanceEdit:3597627] Jin, Lei, 2013-05-21
[InstanceEdit:3597624] Wu, Jiaxi, 2013-05-21
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:3654263] R-HSA-3134821.3
summation[Summation:3222278] DNA-dependent serine/threonine protein kinase DNA-PK is a DN...
(hasEvent)[Pathway:1834949] Cytosolic sensors of pathogen-associated DNA [Homo sapiens]
(updatedInstance)[_UpdateTracker:9780604] Update Tracker - [Reaction:3134821] DNA-PK binds microbial dsDNA - v62:[add_removeInput]
[Change default viewing format]
No pathways have been reviewed or authored by DNA-PK binds microbial dsDNA (3134821)